Ovarian tissue cryopreservation for emerging primary ovarian insufficiency: expanding indications outside of cancer to preserve fertility and increase access to care

Gornet, Megan E.; Chen, Lucy X.; Christianson, Mindy S.

doi:10.1016/j.fertnstert.2022.09.002

Search citation statements

Order By: Relevance

Paper Sections

Select...

Citation Types

Supporting

Mentioning

Contrasting

Year Published

2023

2025

Publication Types

Select...

Article2

Preprint1

Relationship

Self Cite0

Independent3

Authors

Journals

Cited by 3 publications

References 4 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

Local delivery of platelet-derived factors mitigates ischemia and preserves ovarian function through angiogenic modulation: A personalized regenerative strategy for fertility preservation

Chung,

Yang,

Yang

et al. 2025

Biomaterials

View full text Add to dashboard Cite

Local delivery of platelet-derived factors mitigates ischemia and preserves ovarian function through angiogenic modulation: A personalized regenerative strategy for fertility preservation

Chung,

Yang,

Yang

et al. 2025

Biomaterials

View full text Add to dashboard Cite

Local Delivery of Platelet-Derived Factors Mitigates Ischemia and Preserves Ovarian Function Through Angiogenic Modulation: A Personalized Regenerative Strategy for Fertility Preservation

Chung,

Yang,

Yang

et al. 2023

Preprint

View full text Add to dashboard Cite

Ovarian tissue cryopreservation in the pediatric with rare diseases- experience from China’s first and the largest ovarian tissue cryobank

Ruan

Cheng

et al. 2023

Front. Endocrinol.

View full text Add to dashboard Cite

BackgroundThere is limited information about the efficacy of ovarian tissue cryopreservation (OTC) in children. In the present study, we report eight patients with rare diseases who underwent OTC in China’s first and largest ovarian tissue cryobank.ProcedureData from girls with rare diseases who underwent OTC between September 2020 and November 2022 were retrospectively analyzed. We also compared the number of cryopreserved cortex pieces, follicle number, and AMH in those with rare diseases and age-matched children with non-rare diseases who also underwent OTC in our cryobank.ResultsThe median age of the children was 5.88 ± 3.52 (range 2-13) years old. Unilateral oophorectomy was undertaken via laparoscopy in all of the children. The diseases in the 8 patients were: 4 mucopolysaccharidoses (MPS I two cases, IVA two cases), 1 Diamond-Blackfan anemia (DBA), 1 Fanconi anemia (FA), 1 hyperimmunoglobulin E syndrome (HIES), 1 Niemann-Pick disease. The number of cryopreserved cortex pieces was 17.13 ± 6.36, and the follicle count per 2 mm biopsy was 447.38 ± 524.35. No significant difference in age, the count of cryopreserved cortex pieces, follicle number per 2 mm biopsy, and AMH level was seen between the 20 children with non-rare diseases and those with rare diseases.ConclusionsThe reports help practitioners counsel girls with rare diseases about fertility preservation. The demand for OTC in pediatrics will likely grow as a standard of care.

show abstract

Ovarian tissue cryopreservation for emerging primary ovarian insufficiency: expanding indications outside of cancer to preserve fertility and increase access to care

Cited by 3 publications

References 4 publications

Local delivery of platelet-derived factors mitigates ischemia and preserves ovarian function through angiogenic modulation: A personalized regenerative strategy for fertility preservation

Local delivery of platelet-derived factors mitigates ischemia and preserves ovarian function through angiogenic modulation: A personalized regenerative strategy for fertility preservation

Local Delivery of Platelet-Derived Factors Mitigates Ischemia and Preserves Ovarian Function Through Angiogenic Modulation: A Personalized Regenerative Strategy for Fertility Preservation

Ovarian tissue cryopreservation in the pediatric with rare diseases- experience from China’s first and the largest ovarian tissue cryobank

Contact Info

Product

Resources

About