Over‐oxygenation in the acute hospital setting: an implementation failure in need of an implementation science solution

Smallwood, Natasha; Holland, Anne E

doi:10.1111/imj.15326

Internal Medicine Journal

2021

DOI: 10.1111/imj.15326

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Over‐oxygenation in the acute hospital setting: an implementation failure in need of an implementation science solution

Natasha Smallwood

Anne E Holland

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“…More importantly, there is a risk of hyperoxygenation, which has been shown to increase barotrauma 6 and is associated with decreased ventilator-free days and increased mortality. 7 Furthermore, hyperoxia worsens outcomes after myocardial infarction and strokes. Therefore, for F IO 2 to be a useful metric, it has to be tailored to an S aO 2 /S pO 2 of 90%-95%.…”

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confidence: 99%

F_IO₂: An Inspired Solution for a Universal Problem

Sampson

Khan

Kinsky³

2021

Respir Care

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Early recognition of pulmonary dysfunction is critical in accurately and rapidly diagnosing respiratory illnesses such as acute hypoxic respiratory failure, ARDS, and communityacquired pneumonia because the prognosis is largely dependent on how soon the treatment is initiated after the diagnosis. Unfortunately, few easily accessible (noninvasive) techniques exist for measuring oxygenation needs. We congratulate Chalmers et al 1 for the study in this issue of RESPIRATORY CARE in which they identified changes in F IO 2 as an early prognostic marker in patients with ARDS and community-acquired pneumonia. Specifically, the investigators examined a cohort of 3,000 subjects with ARDS or community-acquired pneumonia who were admitted to the ICU. The study identified F IO 2 to be easily accessible in electronic health records and, through careful monitoring, F IO 2 trajectory was a predictor of ventilator-free days. 1 P aO 2 /F IO 2 is the primary classification index and the accepted standard for determining the severity of respiratory illness. However, measurements are noncontinuous, require invasive regular arterial blood gas measurements, and are costly and time intensive for respiratory therapists and other clinicians.

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confidence: 99%

F_IO₂: An Inspired Solution for a Universal Problem

Sampson

Khan

Kinsky³

2021

Respir Care

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Over‐oxygenation in the acute hospital setting: an implementation failure in need of an implementation science solution

Cited by 1 publication

References 22 publications

F_IO₂: An Inspired Solution for a Universal Problem

F_IO₂: An Inspired Solution for a Universal Problem

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Over‐oxygenation in the acute hospital setting: an implementation failure in need of an implementation science solution

Cited by 1 publication

References 22 publications

FIO2: An Inspired Solution for a Universal Problem

FIO2: An Inspired Solution for a Universal Problem

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F_IO₂: An Inspired Solution for a Universal Problem

F_IO₂: An Inspired Solution for a Universal Problem