Over-Repair in Closterium: Increased Radioresistance Caused by an Earlier Exposure to Radiation

Howard, Alma; Cowie, F. G.

doi:10.1007/978-3-642-66455-7_24

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Problems With Dna As a Target1

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2003

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Cited by 6 publications

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“…So-called "over-repair" was documented by Bryant [37][38][39] where cells exposed to the second dose had a higher survival than that expected from a simple iso-effect per fraction rule. Howard and Cowie [40] suggested that some process was stimulated by radiation which made the cells more resistant to the second dose. Later studies showing an adaptive response revealed that the first dose necessary to induce the response could be very small [41,42].…”

Section: Problems With Dna As a Targetmentioning

confidence: 99%