Overall survival and extent of surgery in adult versus elderly glioblastoma patients: A population based retrospective study

Abstract

Overall survival of elderly glioblastoma patients treated with surgery and chemo-irradiation with concomitant and adjuvant temozolomide is significantly reduced compared to the younger patients. In addition, in the elderly the extent of surgery did not influence the prognosis in our population.

Analysis of Treatment Tolerance and Factors Associated with Overall Survival in Elderly Patients with Glioblastoma

“…5 Many clinicians have therefore questioned whether the most common treatment for glioblastoma is appropriate in this apparently weaker population. [6][7][8] In this study, we present data resulting from an analysis of 70 glioblastoma patients who were 60 years old or older. We evaluated their clinical features, immunohistochemical characteristics, treatments, and outcomes to identify factors that are associated with overall survival times, and we further explored whether aggressive treatment is well tolerated in this population.…”