2023
DOI: 10.3390/antibiotics12081230
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Overcoming Drug Resistance in a Clinical C. albicans Strain Using Photoactivated Curcumin as an Adjuvant

Abstract: The limited antifungal drugs available and the rise of multidrug-resistant Candida species have made the efforts to improve antifungal therapies paramount. To this end, our research focused on the effect of a combined treatment between chemical and photodynamic therapy (PDT) towards a fluconazole-resistant clinical Candida albicans strain. The co-treatment of PDT and curcumin in various doses with fluconazole (FLC) had an inhibitory effect on the growth of the FLC-resistant hospital strain of C. albicans in bo… Show more

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“…The dishes were kept at 4ºC for 2h to allow diffusion and then incubated for 24h at 37ºC. Antimicrobial activity was determined by measuring the diameters of inhibition zones [19,20].…”
Section: The Antimicrobial Activity Of Magnolia Officinalis Essential...mentioning
confidence: 99%
“…The dishes were kept at 4ºC for 2h to allow diffusion and then incubated for 24h at 37ºC. Antimicrobial activity was determined by measuring the diameters of inhibition zones [19,20].…”
Section: The Antimicrobial Activity Of Magnolia Officinalis Essential...mentioning
confidence: 99%