2023
DOI: 10.1101/2023.05.15.540824
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Overcoming the speed limit of four‐way DNA branch migration with bulges in toeholds

Abstract: Dynamic DNA nanotechnology involves the use of DNA strands to create programmable reaction networks and nanodevices. The key reaction in dynamic DNA nanotechnology is the exchange of DNA strands between different molecular species, which is achieved through three‐way and four‐ way DNA exchange reactions. While both of these reactions have been widely used to build reaction circuits, the four‐way exchange reaction has traditionally been slower and less efficient than the three‐way reaction. In this paper, we de… Show more

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