Threads are the main constituents of prominences. They are dynamic structures that display oscillations, usually interpreted as magnetohydrodynamic (MHD) waves. Moreover, instabilities such as the Kelvin-Helmholtz instability (KHI) have also been reported in prominences. Both waves and instabilities may affect the thermodynamic state of the threads. e n waves. We study the heating in the partially ionized prominence plasma as well as possible observational signatures of this dynamics. e n waves. We numerically solved the three-dimensional (3D) MHD equations to study the temporal evolution in both ideal and dissipative scenarios. In addition, we performed forward modeling to calculate the synthetic Halpha imaging. e n waves undergo phase-mixing owing to the radially nonuniform density. The phase-mixing generates azimuthal shear flows, which eventually trigger the KHI and, subsequently, turbulence. When nonideal effects are included, the obtained plasma heating is very localized in an annulus region at the thread boundary and does not increase the temperature in the cool core. Instead, the average temperature in the thread decreases owing to the mixing of internal and external plasmas. In the synthetic observations, first we observe periodic pulsations in the Halpha intensity caused by the integration of the phase-mixing flows along the line of sight. Later, fine strands that may be associated with the KHI vortices are seen in the synthetic Halpha images. e n waves in prominence threads after the triggering of the KHI, although this mechanism is not enough to heat such structures. Both the phase-mixing stage and the turbulent stage of the simulated dynamics could be discernible in high-resolution Halpha observations.