Overdiagnosis, Overtreatment or Oversurveillance of Melanoma: Is There a Way Out?

Zalaudek, Iris

doi:10.5826/dpc.1304a250

Cited by 2 publications

(1 citation statement)

References 9 publications

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“…Betz-Stablein et al recommend combining clinical information, total body photography, sequential dermoscopy images and whole slide pathology images associated by artificial intelligence (AI) to increase diagnostic accuracy and decrease the rate of overdiagnosis ( 9 ). To date, no healthcare provider should ever take the risk of not excising a lesion just because of the fear of overdiagnosis, as long as the available evidence is insufficient to predict the outcome of the tumor ( 9 , 15 ).…”

Section: Introductionmentioning

confidence: 99%

The effects of the COVID-19 pandemic on the diagnosis and prognosis of melanoma 2 years after the pandemic in two Romanian counties

Apostu,

Vesa,

Frățilă

et al. 2024

Front. Med.

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BackgroundThe COVID-19 pandemic disrupted the healthcare system and negatively affected the diagnosis and management of melanoma worldwide. The purpose of this study is to investigate the long-term effects of the COVID-19 pandemic on the diagnosis and prognosis of melanoma.Materials and methodsThis retrospective cohort study included histopathologically confirmed melanoma cases from March 2019 to February 2023 in Cluj and Bihor counties. Data from the post-COVID-19 period (March 2021 to February 2023) were compared to the pre-COVID-19 period (March 2019 to February 2020) and the COVID-19 period (March 2020 to February 2021). Patient characteristics, monthly diagnostics, histological subtypes, and key histological features were analyzed using statistical tests.ResultsThe number of melanoma cases diagnosed annually decreased by 31.37 and 23.75% in the first and second post-pandemic years, respectively, compared to pre-pandemic numbers. Diagnostic rates also decreased by 14.9 and 5.4% in the first and second post-pandemic years, respectively, compared to the pandemic period. Prognostic factors worsened in the post-pandemic period, with higher Breslow index and mitotic rate, and increased ulceration and thick melanomas compared to the pre-pandemic period.ConclusionThe COVID-19 pandemic had a long-lasting impact on the diagnosis of melanoma in Romania, resulting in advanced stages and unfavorable prognostic factors. Larger global studies are needed to comprehensively understand the pandemic’s long-term effects on the diagnosis of melanoma.

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Section: Introductionmentioning

confidence: 99%

The effects of the COVID-19 pandemic on the diagnosis and prognosis of melanoma 2 years after the pandemic in two Romanian counties

Apostu,

Vesa,

Frățilă

et al. 2024

Front. Med.

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Prediction of melanoma metastasis using dermatoscopy deep features: an international multicentre cohort study

Lallas,

Spyridonos,

Kittler

et al. 2024

British Journal of Dermatology

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Whether dermatoscopy deep features could serve as biomarker for the prediction of melanoma metastasis, remains an underexplored area in medical research. In this cohort of 712 patients from ten centers from 3 different continents, a support vector machine (SVM) classifier, analyzing deep features from dermatoscopic images, demonstrated similar prognostic performance for metastasis, in terms of AUC and true positive rate, to current benchmarks of melanoma staging, namely Breslow thickness and ulceration. Deep features derived from dermatoscopy could predict, at the time of diagnosis, early-stage melanomas with high metastatic potential, tailoring further treatment strategies.

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Overdiagnosis, Overtreatment or Oversurveillance of Melanoma: Is There a Way Out?

Cited by 2 publications

References 9 publications

The effects of the COVID-19 pandemic on the diagnosis and prognosis of melanoma 2 years after the pandemic in two Romanian counties

The effects of the COVID-19 pandemic on the diagnosis and prognosis of melanoma 2 years after the pandemic in two Romanian counties

Prediction of melanoma metastasis using dermatoscopy deep features: an international multicentre cohort study

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