Feminist/queer science offers exciting possibilities for psychology and other fields. In this article, we review a set of dynamic principles for feminist/queer science, based in research with gender, sex, and sexuality (gender/sex/uality). There are potentially surprising ways that queer and science overlap for a queer science, and we focus on four: construction, openness, challenge, and multiplicities. There are also meeting points between feminism and science that support a feminist science, and we again focus on four: bias, truth, objectivity, and empiricism. Yet there are a number of challenges to feminist/queer science, including those that are epistemological, empirical, and methodological. We detail these, articulating how feminist/queer science also provides ways to address, sidestep, and move beyond them. Throughout, we articulate how feminist/queer science provides a dynamic and rigorous way forward for psychological science as well as other fields, and we conclude by articulating how it can lead to more empirical, accurate, and just knowledge.