2023
DOI: 10.1007/s00436-023-08010-2
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Overexpression of cytochrome P450 and esterase genes involved in permethrin resistance in larvae and adults of Culex quinquefasciatus

Govindaraju Ramkumar,
Ranganathan Muthusamy,
Mathiyazhagan Narayanan
et al.

Abstract: Mosquitoes are the important vectors of several arthropod diseases, which remain a prioritized domain for epidemiology research. Mosquito vector control strategies have classically relied on adult management using chemical insecticides like synthetic pyrethroids. The indiscriminate and non-judicial practice of pesticides has caused tolerance of mosquito population to insecticides of choice. The evolvement of tolerance relies on the expression of few orinterplay of many gene products, belonging to cytochrome P4… Show more

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Cited by 6 publications
(1 citation statement)
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“…funestus [8,9], cu cular resistance [10], behavioural resistance [11] and metabolic resistance. Metabolic resistance acts through metabolism or sequestra on of insec cides by metabolic enzymes majorly the cytochrome P450s, Glutathione S transferases and Carboxylesterases clusters [12][13][14]. However, there are substan al varia ons in the resistance pa erns and its underlying mechanisms across different African regions including Cameroon [15][16][17].…”
Section: Introduc Onmentioning
confidence: 99%
“…funestus [8,9], cu cular resistance [10], behavioural resistance [11] and metabolic resistance. Metabolic resistance acts through metabolism or sequestra on of insec cides by metabolic enzymes majorly the cytochrome P450s, Glutathione S transferases and Carboxylesterases clusters [12][13][14]. However, there are substan al varia ons in the resistance pa erns and its underlying mechanisms across different African regions including Cameroon [15][16][17].…”
Section: Introduc Onmentioning
confidence: 99%