2019
DOI: 10.3233/cbm-190450
|View full text |Cite
|
Sign up to set email alerts
|

Overexpression of P4HB is correlated with poor prognosis in human clear cell renal cell carcinoma

Help me understand this report

Search citation statements

Order By: Relevance

Paper Sections

Select...
1
1
1
1

Citation Types

3
24
0

Year Published

2020
2020
2024
2024

Publication Types

Select...
8

Relationship

2
6

Authors

Journals

citations
Cited by 28 publications
(27 citation statements)
references
References 20 publications
3
24
0
Order By: Relevance
“…20 P4HB is highly expressed in renal clear cell carcinoma (ccRCC) and positively correlated with pathological grade, stage and poor prognosis; it has been verified as an independent risk factor by multifactor Cox regression in ccRCC. 14 In addition, logistic regression and chi-square tests were conducted in 80 BC patients and TCGA database patients and indicated that P4HB overexpression in tissues is strongly associated with the clinicopathological characteristics of BC. Most importantly, BC patients with higher P4HB expression had a worse prognosis than those with lower expression.…”
Section: Discussionmentioning
confidence: 99%
See 2 more Smart Citations
“…20 P4HB is highly expressed in renal clear cell carcinoma (ccRCC) and positively correlated with pathological grade, stage and poor prognosis; it has been verified as an independent risk factor by multifactor Cox regression in ccRCC. 14 In addition, logistic regression and chi-square tests were conducted in 80 BC patients and TCGA database patients and indicated that P4HB overexpression in tissues is strongly associated with the clinicopathological characteristics of BC. Most importantly, BC patients with higher P4HB expression had a worse prognosis than those with lower expression.…”
Section: Discussionmentioning
confidence: 99%
“…The final score was obtained by multiplying the staining intensity score and the staining proportion score. BC patients were categorized as either the low P4HB expression group (1)(2)(3)(4)(5)(6)(7)(8) or the high P4HB expression group (9)(10)(11)(12)(13)(14)(15)(16).…”
Section: Tcga Database Analysismentioning
confidence: 99%
See 1 more Smart Citation
“…The multiplication of these two variables was calculated as a final score: 0 (score 0-3); 1 (score 4-6); 2 (score 7-9); or 3 (score 10-12). 14…”
Section: Immunohistochemistry (Ihc)mentioning
confidence: 99%
“…The staining intensity was classified as 0 (no staining), 1 (weak), 2 (moderate) or 3 (strong); The proportion of stained tumor cells was scored as 0 (0-5%), 1 (6-25%), 2 (26-50%), 3 (51-75%), 4 (>75%). The product of these two variables was used to calculate a final score based on a previous study (26), as follows: 0 (product of 0-3); 1 (product of 4-6); 2 (product of 7-9); 3 (product of 10-12).…”
Section: Extraction Of Clinical and Gene Expression Data From The Ccrmentioning
confidence: 99%