Overlap of Gastrointestinal Symptom Complexes in the Community

Locke, Richard G.; Zinsmeister, Alan R.; Melton, Joseph L.; Talley, Nicholas J.

doi:10.1111/j.1572-0241.2003.08560.x

Cited by 36 publications

(40 citation statements)

References 0 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Using a retrospective chart review in which the common symptoms of upper and lower GI motility were considered as being present or absent, the authors again failed to find significant correlations between these two variables, in concordance with previous studies [7,8]. The authors thus concluded that WMC testing is useful for characterizing multiregional dysmotility, and in distinguishing between patients with a functional disorder and those with motility disorders, also documenting that symptoms were poor predictors of the anatomical regions affected by dysmotility.…”

supporting

confidence: 75%

Connecting the Dots Between Gastrointestinal Motility and Symptoms Using Wireless Motility Capsule Testing

Barshop

Kuo

2015

Dig Dis Sci

View full text Add to dashboard Cite

supporting

confidence: 75%

Connecting the Dots Between Gastrointestinal Motility and Symptoms Using Wireless Motility Capsule Testing

Barshop

Kuo

2015

Dig Dis Sci

View full text Add to dashboard Cite

“…In gastroptosis subjects, ingested food could be retained in the gastric body like swallowed barium. In patients with GERD and FD, dyspeptic symptoms overlap (18), and these conditions are not easily distinguished. Because TLESR, gastric emptying, and gastric accommodation are closely interrelated, conditions like gastroptosis that affect gastric capacity for ingested food, fluid, and air could be important.…”

Section: Discussionmentioning

confidence: 99%

Gastroptosis is Associated with Less Dyspepsia, Rather than a Cause of Dyspepsia, in Japanese Persons

et al. 2011

View full text Add to dashboard Cite

Objective Gastroptosis is recognized by its characteristic appearance on barium studies. The present prospective study assessed the relationship between gastroptosis and dyspeptic symptoms. Methods Japanese subjects underwent health screening, and gastroptosis was diagnosed by barium studies. Consecutive subjects (500 women and 167 men) with gastroptosis were identified and the same number of age-matched subjects without gastroptosis were selected as controls. Dyspepsia was classified as reflux-like (heartburn and belching), dysmotility-like (bloating and fullness), or ulcer-like dyspepsia (epigastralgia) based on the Rome II criteria. Results Body mass index was significantly lower in women with gastroptosis than in controls [19.7±1.83 (SD) vs. 23.4±3.70, p<0.0001], and also in men (19.7±2.00 vs. 23.9±2.89, p<0.0001). The incidence of dyspepsia was significantly lower in women with gastroptosis than in controls (56/500 vs.87/500, p<0.01) and also in men (10/167 vs. 25/167, p<0.05), especially in women with ulcer-like dyspepsia (15/500 vs. 32/500, p<0.05) and in men with reflux-like dyspepsia (2/167 vs. 12/167, p<0.05). By logistic regression analysis, gastroptosis was associated with a lower risk of dyspepsia (odds ratio: 0.62, 95% CI: 0.405-0.941, p=0.025) and ulcer-like dyspepsia (odds ratio: 0.36, 95% CI: 0.177-0.726, p=0.004) in women. Conclusion Dyspeptic symptoms were significantly less common in subjects with gastroptosis. Accordingly, gastroptosis may protect against dyspeptic symptoms, rather than causing functional dyspepsia.

show abstract

“…Recent studies have reported on the considerable overlap of different GI symptoms in patients seeking medical attention [11,12] . The first available report on this relationship indicate that around 30% of IBS patients have daily heartburn and almost 60% have monthly heartburn [13] .…”

Section: Discussionmentioning

confidence: 99%

Dyspepsia and IBS Symptoms in Patients with NERD, ERD and Barrett’s Esophagus

Neumann

Mönkemüller

Kandulski

et al. 2008

Dig Dis

View full text Add to dashboard Cite

Introduction: Irritable bowel syndrome (IBS) and functional dyspepsia (FD) are highly prevalent in the general population as does gastroesophageal reflux disease (GERD). Therefore, it is expected that these conditions may frequently overlap. Objective: We aimed at evaluating the presence ofFD and IBS symptoms in patients with erosive (ERD), non-erosive reflux disease (NERD) and Barrett’s esophagus (BE). Patients and Methods: 71 patients presenting at the reflux disease outpatient clinic were prospectively included in this study. 33 patients had NERD, 25 ERD and 13 BE according to the Montreal classification. All patients with ERD and NERD had typical reflux symptoms, as assessed by a validated GERD questionnaire (RDQ). The diagnosis of functional dyspepsia and IBS symptoms was assessed according to the Rome III criteria. Results: IBS symptoms (bloating, abdominal pain, constipation and diarrhea) were slightly more prevalent in NERD (54.6, 63.6, 21.20, 24.2%, respectively) than in ERD (48.0, 44.0, 12.0, 20.0%, respectively) and in BE (53.9, 23.10, 15,4, 23.1%, respectively), but none of these differences reached statistical significance. NERD patients had more FD symptoms than patients with ERD or BE, but again this difference did not reach statistical significance. Conclusion: Our data show that IBS and FD are common in the entire spectrum of GERD. The presence of these disorders might explain why many patients with GERD are deemed as treatment failures if they have no complete symptom relief with proton pump inhibitors.

show abstract

Overlap of Gastrointestinal Symptom Complexes in the Community

Cited by 36 publications

References 0 publications

Connecting the Dots Between Gastrointestinal Motility and Symptoms Using Wireless Motility Capsule Testing

Connecting the Dots Between Gastrointestinal Motility and Symptoms Using Wireless Motility Capsule Testing

Gastroptosis is Associated with Less Dyspepsia, Rather than a Cause of Dyspepsia, in Japanese Persons

Dyspepsia and IBS Symptoms in Patients with NERD, ERD and Barrett’s Esophagus

Contact Info

Product

Resources

About