Overlapping palindromic sequences associated with somatic deletion and meiotic recombination of MHC class I genes

Vogel, Julie M.; Nieto, Maria C.; Fischer, Ann; Goodenow, Robert S.

doi:10.1016/0161-5890(90)90154-r

Cited by 9 publications

(5 citation statements)

References 37 publications

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“…Both characteristics are also responsible for the ability of DNA sequences to acquire secondary structures, such as cruciforms (stems or stems and loops, respectively). It has been postulated that these types of structures could be involved in recombination events (Israelewski, 1983;Higgins et al, 1988;Vogel et al, 1990) or in DNA amplification processes (Bigot et al, 1990;Oshima et al, 1992). In addition, these structures could be involved in chromatin organization as sites recognized by specific proteins, as in the case of HMG-I protein (Rodriguez-Alfageme et al, 1980).…”

Section: Discussionmentioning

confidence: 99%

A satellite DNA of the Sparidae family (Pisces, Perciformes) associated with telomeric sequences

R²,

Rejón³

et al. 1998

Cytogenet Genome Res

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This paper reports on the isolation and localization of the subtelomeric DraI satellite DNA in the Sparidae family. Gene cloning determined that the DraI satellite DNA is present in only 3 species (Pagrus pagrus, P. auriga, and Pagellus erythrinus) of the 10 Sparidae species analyzed. The results were confirmed by PCR amplification. This satellite DNA is located in a subtelomeric position in all 48 acrocentric chromosomes of these species. However, interstitial loci are also observed. Sequence analysis of monomers of this repetitive family indicates that the satellite DNA is associated with telomeric sequences, (TTAGGG)_n, in at least one species, P. erythrinus. This is the first direct demonstration of the existence of the consensus telomere sequences of vertebrates in fish. Likewise, this report also demonstrates that the ends of fish chromosomes have a structure similar to those of most eukaryote chromosomes, viz., telomere sequences and subtelomeric sequences associated by a boundary in which both types of sequences are interspersed. The recent origin of the DraI satellite DNA and its use as a phylogenetic marker is discussed.

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Section: Discussionmentioning

confidence: 99%

A satellite DNA of the Sparidae family (Pisces, Perciformes) associated with telomeric sequences

R²,

Rejón³

et al. 1998

Cytogenet Genome Res

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“…They have been shown to increase recombination (Anderson and Roth 1978;Warren and Green 1985;Higgins et al 1988) andDNA amplification (Cohen andKopecko 1976). They are known to occur at sites of DNA breakage associated with gene conversion, nonhomologous recombination, and sister chromatid exchange (Israelewski 1983;Henthorn et al 1986;Krawinkel et al t986;Hyrien et al 1987;Vogel et al 1990) and may affect chromosome structure (Gilson et al 1986;Ohno 1990) or pairing (Sobell 1972;Doyle 1978).…”

Section: Discussionmentioning

confidence: 99%

Junctions between repetitive DNAs on the PSR chromosome of Nasonia vitripennis: Association of palindromes with recombination

et al. 1994

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The Paternal-Sex-Ratio (PSR) chromosome of Nasonia vitripennis contains several families of repetitive DNAs that show significant sequence divergence but share two palindromic regions. This study reports on the analysis of junctions between two of these repetitive DNA families (psr2 and psr18). Three lambda clones that hybridized to both repeat families were isolated from PSR-genomic DNA libraries through multiple screenings and analyzed by Southern blots. Analysis of clones showed a region in which the two repeat types are interspersed, flanked by uniform blocks of each repeat type. PCR amplification of genomic DNA confirmed the contiguous arrangement of psr2 and psr18 on PSR and identified an additional junction region between these repeats that was not present in the lambda inserts. We isolated and sequenced 41 clones from the lambda inserts and genomic PCR products containing junction sequences. Sequence analysis showed that all transitions between psr2 and psr18 repeats occurred near one of the two palindromes. Based on the inheritance pattern of PSR, recombination between repeats on this chromosome must be mitotic (rather than meiotic) in origin. The occurrence of exchanges near the palindromes suggests that these sequences enhance recombination between repeat units. Rapid amplification of repetitive DNA may have been an important factor in the evolution of the PSR chromosome.

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“…For example, a G/CTT consensus sequence for topoisomerase I is found in certain eukaryote loop structures where single-stranded DNA cleavage occurs. The formation of hairpin structures in B chromosomes may attract DNases (Vogel et al 1990), and expose enough single-stranded DNA to induce single-stranded cleavage and chromosome breakage, predisposing them to chromosomal rearrangements.…”

Section: (D) Epigenetic Changes In B Chromosomesmentioning

confidence: 99%

B-chromosome evolution

Camacho

Sharbel

Beukeboom

2000

Phil. Trans. R. Soc. Lond. B

582

631

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B chromosomes are extra chromosomes to the standard complement that occur in many organisms. They can originate in a number of ways including derivation from autosomes and sex chromosomes in intra- and interspecies crosses. Their subsequent molecular evolution resembles that of univalent sex chromosomes, which involves gene silencing, heterochromatinization and the accumulation of repetitive DNA and transposons. B-chromosome frequencies in populations result from a balance between their transmission rates and their effects on host fitness. Their long-term evolution is considered to be the outcome of selection on the host genome to eliminate B chromosomes or suppress their effects and on the B chromosome's ability to escape through the generation of new variants. Because B chromosomes interact with the standard chromosomes, they can play an important role in genome evolution and may be useful for studying molecular evolutionary processes.

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Overlapping palindromic sequences associated with somatic deletion and meiotic recombination of MHC class I genes

Cited by 9 publications

References 37 publications

A satellite DNA of the Sparidae family (Pisces, Perciformes) associated with telomeric sequences

A satellite DNA of the Sparidae family (Pisces, Perciformes) associated with telomeric sequences

Junctions between repetitive DNAs on the PSR chromosome of Nasonia vitripennis: Association of palindromes with recombination

B-chromosome evolution

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