Overview of anaphylaxis in Korea: diagnosis and management

Jang, Gwang Cheon; Chang, Yoon-Seok; Choi, Sun Hee; Song, Woo Jung; Lee, Soo Young; Park, Hae‐Sim; Kang, Hye Ryun; Ye, Yeong Min; Jin, Hyun Jung; Shin, Mi Yong; Lee, Soo Jin; Kim, Hye One; Kim, Jihyun; Jung, Jae Woo; Moon, Hee Bom; Ahn, Young‐Min

doi:10.4168/aard.2013.1.3.181

Cited by 27 publications

(7 citation statements)

References 78 publications

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“…However, the majority of studies showed that the most common cause was food [ 11 , 13 , 14 , 17 , 18 ]. Major food allergen categories and their rates of sensitivity are variable depending on the difference in dietary habits according to race and region [ 5 , 10 ]. Notably, among the foods that induced anaphylaxis, different patterns were observed.…”

Section: Discussionmentioning

confidence: 99%

“…These are explained by an IgE-mediated reaction that activates mast cells or basophils that secrete chemical media [ 1 , 2 , 3 ]. However, anaphylaxis has been used clinically in a broader sense including anaphylactic reactions that are similar to or manifested by anaphylactic reactions due to nonimmune mechanisms, as well as by immunological mechanisms [ 4 , 5 ]. The prevalence rate is known to be 0.05–2% [ 4 ] outside Korea, and within the country, it is reported to be 0.014% [ 6 , 7 ].…”

Section: Introductionmentioning

confidence: 99%

“…At a university hospital in Suwon, 11 years of data on 158 patients reported the causes of anaphylaxis as drugs (51.2%), insect bites (25.3%), food (10.8%), and exercise (6.3%) [ 7 ]. There are numerous causes of anaphylaxis, and there are variable clinical responses, even with the same cause [ 5 ]. This means that, in reality, the study of anaphylaxis is not easy, and there are not many reports in the literature from practice [ 6 , 7 , 8 , 9 , 10 , 11 , 12 , 13 , 14 , 15 , 16 , 17 , 18 ].…”

Section: Introductionmentioning

confidence: 99%

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Anaphylaxis: Five Years’ Experience in the Emergency Rooms of Five University Hospitals in Korea

Chung

Kim

et al. 2020

Medicina

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Background: Anaphylaxis is an allergic disease that requires special handling due to its potential fatality. Recent epidemiological data indicate that the incidence of anaphylaxis is rising. However, actual data on the prevalence or causes of anaphylaxis in Korea are limited. Methods: The emergency room attendees diagnosed with anaphylaxis between 2011 and 2015 in five university hospitals were included. Medical records were reviewed retrospectively. Results: During the 5 years, a total of 505 subjects were diagnosed with anaphylaxis. Respiratory presentations were more common in children than in adults, while adults presented more frequently with cardiovascular symptoms. Intraoral angioedema was more often observed in the countryside than in the city. Insect stings/bites were more common in the countryside than in the city. Drugs were much more common in adults than in children. In the countryside, the frequency of anaphylaxis was higher in summer and autumn than in spring and winter. The use of corticosteroids was less common in children than in adults, while children more frequently got treatment with inhaled beta 2 agonist. Conclusions: The principal causes of anaphylaxis in Korean patients were food, drugs, and stings/bites. The cause, clinical features and management of anaphylaxis were significantly different depending on age and region. These real-world data on anaphylaxis could be helpful to deepen that understanding of this condition for physicians and patients.

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Section: Discussionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

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Anaphylaxis: Five Years’ Experience in the Emergency Rooms of Five University Hospitals in Korea

Chung

Kim

et al. 2020

Medicina

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“…Past medical history included previous allergies (asthma, allergic rhinitis, atopic dermatitis, or food allergy), and other health conditions (hypertension, diabetes, heart disease, respiratory disease, or skin disease), exposure to stings, current use of oral antibiotics (cefotiam, rifampin, cefaclor, ampicillin, amoxicillin, quinolone, vancomycin, erythromycin, or aminoglycoside), aspirin, nonsteroidal anti-inflammatory drugs [6], angiotensinconverting enzyme inhibitor drugs, and beta blockers or alpha blockers. All these factors may contribute toward the development of an allergic reaction to BV [8,9].…”

Section: Past Medical Historymentioning

confidence: 99%

“…Despite the effectiveness of BV pharmacopuncture, the pharmacological effects of BV may cause an allergic reaction in some individuals which may be mild or severe [6]. Mild symptoms are observed on the surface of the skin and in subcutaneous tissue.…”

Section: Introductionmentioning

confidence: 99%

A Retrospective Study on the Clinical Safety of Bee Venom Pharmacopuncture at Craniofacial Acupuncture Points for the Treatment of Facial Disorders

et al. 2019

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Background: This study was designed to evaluate the clinical safety of Bee Venom (BV) pharmacopuncture at craniofacial acupuncture points. Methods: This was a retrospective study of 108 patients diagnosed with peripheral facial paralysis, trigeminal neuralgia, or facial spasm who were admitted to Kyung Hee University Korean Medicine Hospital at Gangdong, from April 1st, 2017 to August 30th, 2017. Patients were allocated into either, Group 1 (the non-allergy group of patients who did not have an allergic reaction to BV) or Group 2, the group who had allergic reactions to BV. To evaluate the clinical safety of BV pharmacopuncture after each treatment, several criteria were used to measure any side effects: outcome, Common Terminology Criteria for Adverse Events scale, Mueller HL scale, treatment decision after adverse reaction, causality, measures performed for patients with adverse reactions, and efficacy assessment. Results: BV pharmacopuncture delivered in 0.1-0.2 mL at a concentration of 1:30,000 at the craniofacial acupuncture points, showed no statistically significant differences in baseline characteristics between non-allergy Group 1 and allergy Group 2. Amongst the 108 patients, 11 reported side effects after BV pharmacopuncture treatment. These adverse events included rash (n = 7), pruritus (n = 5), swelling (n = 1), vesicles (n = 1), erythema (n = 1), and hives (n = 1). All side effects resolved without sequelae. Conclusion: In this study, BV pharmacopuncture delivered at low doses at the craniofacial acupuncture points, resulted in 10% of patients experiencing non serious side effects suggesting that BV pharmacopuncture was clinically well tolerated.

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Development and Evaluation of a Mobile Web-based Food Allergy and Anaphylaxis Management Educational Program for Parents of School-aged Children with Food Allergy: A Randomized Controlled Trial

Kwen

2022

Asian Nursing Research

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Overview of anaphylaxis in Korea: diagnosis and management

Cited by 27 publications

References 78 publications

Anaphylaxis: Five Years’ Experience in the Emergency Rooms of Five University Hospitals in Korea

Anaphylaxis: Five Years’ Experience in the Emergency Rooms of Five University Hospitals in Korea

A Retrospective Study on the Clinical Safety of Bee Venom Pharmacopuncture at Craniofacial Acupuncture Points for the Treatment of Facial Disorders

Development and Evaluation of a Mobile Web-based Food Allergy and Anaphylaxis Management Educational Program for Parents of School-aged Children with Food Allergy: A Randomized Controlled Trial

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