Fluid–structure coupled simulations are performed for quasi-steady pitching maneuvers of a large transport aircraft with a load alleviation system consisting of trailing edge flaps and droop noses at the leading edge. For the fluid part of the simulation, a RANS approach is used, whereas the structural simulation is based on a linear modal model. The selected maneuvers are located on the lift boundary of the maneuver envelope at maximum load factor, as not only are the structural loads high here, but also redistributing lift for load alleviation is especially challenging as the wing is close to stall. For a target value of 33% reduction in wing bending loads, which is derived from the CS-25, the effects of applying load alleviation on wing loads, deformations, and aircraft maneuverability are investigated. It is found that the desired reduction of wing bending loads can be achieved for all maneuvers considered, while controlling the torsional moment turns out to be more difficult. A loss of maneuverability due to load alleviation is observed for only one of the maneuvers, while for the other maneuvers, maneuverability could even be increased. To assess the influence of the elasticity of the wing, additional simulations of the rigid wing are carried out and compared with the elastic results. Finally, other potential applications of the considered flap system are also explored. Here, for example, a cruise drag reduction of up to 1.8% is possible by adjusting the spanwise lift distribution.