2017
DOI: 10.21037/acs.2017.03.03
|View full text |Cite
|
Sign up to set email alerts
|

Overview of esophageal cancer

Abstract: Esophageal cancer is a male-dominant aggressive malignancy and a leading cause of cancer-related mortality worldwide. Squamous cell carcinoma and adenocarcinoma are the two predominant histological subtypes with varying geographical and racial distribution. Globally, squamous cell carcinoma remains the most common histological type. In Western countries, however, adenocarcinoma has become the leading histological subtype, corresponding to a rise in the incidence of obesity, gastro-esophageal reflux disease and… Show more

Help me understand this report

Search citation statements

Order By: Relevance

Paper Sections

Select...
5

Citation Types

0
180
1
5

Year Published

2017
2017
2024
2024

Publication Types

Select...
8

Relationship

0
8

Authors

Journals

citations
Cited by 181 publications
(186 citation statements)
references
References 41 publications
0
180
1
5
Order By: Relevance
“…Despite recent advances in the diagnosis and treatment of ESCC, the final prognosis remains unsatisfactory. The overall 5‐year survival rate of advance ESCC is about 10%‐20% . The absence of early symptoms, high rates of local invasion, and lymphatic metastasis largely contributes to the unfavorable prognosis of ESCC, thus revealing the underlying mechanism of ESCC and discovery of new drug targets is of vital importance.…”
Section: Introductionmentioning
confidence: 99%
“…Despite recent advances in the diagnosis and treatment of ESCC, the final prognosis remains unsatisfactory. The overall 5‐year survival rate of advance ESCC is about 10%‐20% . The absence of early symptoms, high rates of local invasion, and lymphatic metastasis largely contributes to the unfavorable prognosis of ESCC, thus revealing the underlying mechanism of ESCC and discovery of new drug targets is of vital importance.…”
Section: Introductionmentioning
confidence: 99%
“…Esophageal cancer ranks the 6th cancer‐related death in the world . ESCC is a common tissue subtype of esophageal cancer in Asia, including China .…”
Section: Introductionmentioning
confidence: 99%
“…Esophageal cancer ranks the 6th cancer‐related death in the world . ESCC is a common tissue subtype of esophageal cancer in Asia, including China . Diagnosis at late stage and drug resistance are the main causes for this refractory disease .…”
Section: Introductionmentioning
confidence: 99%
“…5 A similar trend has been reported in other Western countries. 6 Unlike esophageal adenocarcinoma, the incidence does not differ significantly between white and African. 7 Anecdotal reports show that the number of esophageal cancers in the hospitals of Somalia is high, and most of these patients are diagnosed in late stages leading to a loss of the chance for a surgical treatment.…”
Section: Introductionmentioning
confidence: 92%