Primer on the Metabolic Bone Diseases and Disorders of Mineral Metabolism 2013
DOI: 10.1002/9781118453926.ch81
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Overview of Mechanisms in Cancer Metastases to Bone

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“…Several mechanisms of bone metastasis have been suggested: dissemination of cancer cells from the primary tumor; systemic embolization; adherence to bone marrow vascular endothelium; extravasation into the bone marrow environment; and interaction with osteoblasts and/or osteoclasts (2,15,16).…”
Section: Pathomechanism Of Bone Marrow Metastasesmentioning
confidence: 99%
“…Several mechanisms of bone metastasis have been suggested: dissemination of cancer cells from the primary tumor; systemic embolization; adherence to bone marrow vascular endothelium; extravasation into the bone marrow environment; and interaction with osteoblasts and/or osteoclasts (2,15,16).…”
Section: Pathomechanism Of Bone Marrow Metastasesmentioning
confidence: 99%