Overview of Phenylhydrazine‐Based Organic Transformations

Abstract

Phenylhydrazines, comprised of a phenyl group attached with hydrazine unit, contribute potentially to organic synthetic transformations. Because of the myriad of synthetic applications, the last decade has witnessed a considerable upsurge of interest to perform various reactions catalyzed/mediated/promoted by phenylhydrazines. Some of these reactions have shown high regioselectivity in short reaction time under mild reaction conditions. The emergence of innumerable synthetic transformations utilizing phenylhydrazine has unleashed numerous openings for the development of diverse heterocyclic scaffolds. Given the synthetic importance of this valuable chemical entity, this review highlights the methodologies utilizing phenylhydrazines. Moreover, the present article will contribute considerably to the organic synthesis as well as in pharmaceutical chemistry. Academically, this review article will be interesting and informative for the researchers attempting to develop new synthetic routes for the heterocyclic structures.