Overview of regulations on medicines derived from traditional Pharmacopoeia in Benin and Burkina Faso

Dori, Daniel; Ganfon, Habib; Gbaguidi, Fernand; Évrard, Brigitte; Quetin-Leclercq, Joëlle; Semdé, Rasmané

doi:10.22270/ijdra.v7i4.361

Cited by 4 publications

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“…A decree and its implementing order, adopted in 2012 and 2013, define the specific terms of the opening and running of traditional medicine and pharmacopoeia facilities including the production of plant medicines. These terms contain the requirements of good practices of production and the commitment of a responsible pharmacist [20][21][22].…”

Section: Introductionmentioning

confidence: 99%

“…The approval of MDTPs in Benin is regulated by an order n o 2017 017/MS/DC/SGM/CTJ/DPMED/DA/SA016SGG17 of 05/02/2017 laying down procedures for the approval of herbal medicinal products in the Republic of Benin [23]. In Burkina Faso, the approval of these medicines is specifically controlled by the Dec 14, 2004 decree n o 2004-569 /PRES/ PM/MS/MCPEA/MECV/MESSRS and the July 6, 2005 order n o 2005-231/MS/CAB [22,24,25]. This local production is often made by traditional healers or semi-industrial units from plant raw materials [26,27].…”

Section: Introductionmentioning

confidence: 99%

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Study of Manufacturing Conditions of Medicines Derived from Traditional Pharmacopoeia in Benin and Burkina Faso

Dori¹,

Ouedraogo²,

HOUNGUE

et al. 2021

Phytothérapie

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Introduction: Traditional medicine has become an important component in the care system of African populations. Many products derived from it are increasingly used in the therapeutic arsenal. This work is an inventory of the production of these drugs in two countries of West Africa, Burkina Faso and Benin. Methods: A cross-sectional descriptive study that listed the drug manufacturing units producing medicines derived from the traditional pharmacopoeia (MDTP) identified by the health ministries in the two countries was carried out. Results: Thirty-three production facilities, including 10 in Burkina Faso and 23 in Benin, were surveyed. Seven units surveyed in Burkina Faso and 16 in Benin were illegally installed. Only 16 of the 33 units obtain their raw materials from botanical gardens. The rest obtain theirs through picking which is not favorable to the perpetuation of the plant resource. In addition, among the 1041 MDTPs manufactured by the units surveyed, only 1.44% are registered. Finally, shortcomings in applying good practices for harvesting raw materials and manufacturing finished products were noticed. Conclusion: Management and capacity building efforts of MDTPs production facilities by political authorities are still needed to optimize the contribution of traditional medicine to the health care of African populations.

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Section: Introductionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Study of Manufacturing Conditions of Medicines Derived from Traditional Pharmacopoeia in Benin and Burkina Faso

Dori¹,

Ouedraogo²,

HOUNGUE

et al. 2021

Phytothérapie

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Prevalence of traditional medicines use and adverse events: A population-based cross-sectional survey in Burkina Faso

Ouoba¹,

Lehmann²,

Zongo³

et al. 2022

European Journal of Integrative Medicine

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Von der traditionellen Anwendung zur rationalen Phytotherapie: Phytochemische Analyse und prä-klinische Untersuchungen zur antimikrobiellen Wirkung von Blätterextrakten von Combretum collinum Fresen.

Marquardt

Vissiennon

Ahyi³

et al. 2020

Zeitschrift für Phytotherapie

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ZusammenfassungIn der Zone südlich der Sahara gibt es etwa 7000 verschiedene Pflanzenarten, die ein großes Potenzial haben, zur Ernährungs- und Gesundheitsversorgung der 1,2 Milliarden Einwohner dieser Region beizutragen. Besonders in Benin, einem Staat in Westafrika, sind Heilpflanzen eine wichtige natürliche Ressource, die 80–99 % der Bevölkerung mindestens als ergänzende, wenn nicht sogar als primäre medizinische Grundversorgung nutzen. Blätter von Combretum collinum Fresen. (Combretaceae) werden in der traditionellen westafrikanischen Medizin zur Behandlung bakterieller Infektionen und zur Förderung der Wundheilung eingesetzt. Die vorliegende Untersuchung konzentriert sich auf die phytochemische Charakterisierung und die Analyse der antimikrobiellen Aktivität eines 50 % EtOH-Blattextraktes von C. collinum. Untersuchungen zur antimikrobiellen Aktivität wurden mit Agar-Well-Diffusions- und Mikrodilutionstests durchgeführt. Die phytochemische Charakterisierung erfolgte mit verschiedenen chromatographischen und spektroskopischen Methoden (HPLC, LC-MS, Flash-Chromatographie, 1 H-NMR). Die Untersuchungen bestätigten Myricetin-3-O-rhamnosid und Myricetin-3-O-glucosid als polyphenolische Hauptinhaltsstoffe des 50 % EtOH-Blattextraktes von C. collinum. Im Agar-Well-Diffusionstest zeigte der Extrakt die größten Hemmhöfe gegen S. epidermidis, MRSA und S. aureus. Im Mikrodilutionstest wies der Extrakt durchschnittliche Hemmkonzentrationen von 275,0 µg/ml für S. epidermidis und 385,5 µg/ml für MRSA auf. Der Nachweis der antibakteriellen Aktivität liefert einen deutlichen Hinweis für den möglichen Nutzen der topischen Anwendung von Extrakten aus C.-collinum-Blättern in der traditionellen westafrikanischen Medizin. Die ethnomedizinische Verwendung bietet somit eine alternative Behandlungsoption für topische Infektionen durch Staphylococcus-Arten.

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Overview of regulations on medicines derived from traditional Pharmacopoeia in Benin and Burkina Faso

Cited by 4 publications

References 0 publications

Study of Manufacturing Conditions of Medicines Derived from Traditional Pharmacopoeia in Benin and Burkina Faso

Study of Manufacturing Conditions of Medicines Derived from Traditional Pharmacopoeia in Benin and Burkina Faso

Prevalence of traditional medicines use and adverse events: A population-based cross-sectional survey in Burkina Faso

Von der traditionellen Anwendung zur rationalen Phytotherapie: Phytochemische Analyse und prä-klinische Untersuchungen zur antimikrobiellen Wirkung von Blätterextrakten von Combretum collinum Fresen.

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