The experiment was carried out in pots with a capacity of 28 kg in the Department of Horticulture and Landscape Engineering - College of Agriculture - the University of Karbala in order to know the extent of the effect of glutathione and biofertilizer and to determine the best concentration of these treatments in reducing the harmful effect of water stress in terms of the content of enzyme antioxidants and active substances and determine The best irrigation level for this plant without harming the plant and determining the best concentration of glutathione and biofertilizer in reducing the harmful effects of water stress on the Moringa plant, as the study included three factors: glutathione with three concentrations (0, 100, 200) mg. L-1 and biofertilizer (Algacell) at two levels (0 and 10) mg. L-1 and water stress have three field capacity levels (60%, 50%, and 40%). The experiment was carried out using Dunkin’s multinomial test at a probability level of 0.05. The data were analyzed according to the statistical program (SAS 2003), where the results showed that there is a significant effect of glutathione on Most botanical characteristics and mineral element content. Glutathione is an antioxidant that plays a role in plant growth, cell division, and elongation, which protects cells. Water stress affects the dissolution of nutrients and their transfer from soil to plants. The more a plant is exposed to water stress, the more leaves will drop due to the increased ABA concentration. Moreover, the root was longer. Where water stress leads to an increase in the levels of ROS within the plant cells, which stimulates the plant to resist and remove the effect of these free radicals. Moringa is a plant gaining much attention due to its many benefits is a drought-tolerant crop, great for areas lacking water, that can grow in drought-prone regions. It is also a plant that can be used in many different ways, including food, medicine, environmental restoration, and textile products.