“…Utilizing alternative environmentally acceptable eluents to reduce the harmful impacts of toxic solvents on the ecosystem is one of the 12 principles of green analytical chemistry (GAC), which is a method of chemical analysis . A literature search found an exponential rise in the usage of environmentally friendly solvents over the past few decades. − The literature has described a number of approaches to assess the analytical methodologies’ greenness profiles. − To measure greenness profiles, only the Analytical GREEnness (AGREE) technique applies all 12 GAC principles. , As a result, the AGREE approach was used to calculate the greenness profiles of the current method . In comparison to traditional liquid chromatographic techniques, the HPTLC method has a number of benefits, including ease of use, little pretreatment, sensitivity, efficiency, simultaneous analysis of many samples, a nondestructive mode of detection, low solvent consumption, short analysis time, and low cost. , Based on these details and findings, the current approach aims to design and evaluate an environmentally friendly reversed-phase HPTLC strategy for the measurement of TNX in procured tablets and capsules.…”