BESITY IS INCREASINGLY RECognized as a public health epidemic and modifiable risk factor for coronary heart disease (CHD). 1,2 Among adult US women and men, nearly two thirds are overweight and more than one third are obese, and these proportions are rapidly increasing. 1,3 Numerous studies have shown that anthropometric indices including body mass index (BMI), waist circumference, waist-hip ratio, and waist-height ratio are associated with CHD risk factors or adverse events. 4-9 Previous reports have documented that increased cardiovascular (CV) risk associated with being overweight is partially explained by its association with numerous risk mediators, including traditional atheroscle-rotic risk factors, insulin resistance, inflammation, and endothelial dysfunction. 4-7,10 Most obesity studies, however, have not adequately measured physical Author Affiliations are listed at the end of this article.