Owner compliance with short term antimicrobial medication in dogs

Abstract

The degree to which dog owners complied with instructions to administer a 5 to 10 day course of antimicrobial medication to their pets was assessed using microprocessor based monitoring devices. Twenty two clients gave an average of 84% of prescribed doses of amoxycillin-clavulanate. No difference was found between twice and thrice daily dosing regimens in the overall percentage of prescribed doses given. However, timing of doses was far from ideal in many cases and only 34% of doses were given within the designated optimum time period. Adherence to desired dosing intervals tended to be better with twice daily than with thrice daily dosing, although the difference was statistically insignificant.

Evaluation of client compliance with short-term administration of antimicrobials to dogs

“…These findings are in agreement with results of other studies 6,7,21,22 in the human and veterinary literature. Median compliance rates ranged from 64% to 100%, depending on the method of assessment, with the lowest value occurring when compliance was defined as the proportion of doses given on time.…”

Pharmacokinetics of cefovecin sodium after subcutaneous administration to Hermann's tortoises (Testudo hermanni)

“…32 Clearly, when considered from the practical standpoint and for animal well-being, a long duration of effect requiring less frequent drug administration is beneficial because it contributes to reduction of patient stress and helps to optimize owner compliance at the same time. [41][42][43] Especially in nondomestic and wild or feral animals, stress must be considered a very important and limiting factor because these types of animals can be more susceptible to stress caused by repeated handling and restraint. 44 In light of the results of the present pharmacokinetics study, and particularly on the basis of the plasma elimination half-life, it seems that the dosing interval of cefovecin described for dogs and cats (14 days) 21,22 cannot be considered valid for tortoises.…”

Comparison of a new metamizole formulation and carprofen for extended post-operative analgesia in dogs undergoing ovariohysterectomy

“…Carprofen has been studied extensively in dogs in the perioperative (Nolan and Reid, 1993;Fox and Johnston, 1997;Lascelles et al, 1998;Laredo et al, 2004;Shih et al, 2008) and also in the extended post-operative period (Leece et al, 2005). An advantage of carprofen is that it is generally administered only once daily, thereby improving owner compliance (Pullar et al, 1988;Barter et al, 1996).…”