“…A similar degradative series has been demonstrated in chemical studies using strong oxidants or reductants, with proposed radical intermediates causing decarboxylation and subsequent defluorination (Singh et al ., 2019 ; Su et al ., 2019 ; Filho and Souza, 2020 ; Liu et al ., 2021 ; Palma et al ., 2021 ). Given that radical decarboxylation reactions are well known in biological systems (Liu et al ., 2018 , 2018 , 2018 , 2018 ; Michlits et al ., 2020 ; Rodrigues et al ., 2020 ; Pastore et al ., 2021 ), a radical‐based mechanism for perfluorooctanoate was proposed (Wackett and Robinson, 2020 ). Moreover, radical desulfonation enzymology has been described (Peck et al ., 2019 ; Dawson et al ., 2021 ), and radical desulfonation chemistry for PFAS has been described (Niu et al ., 2016 ).…”