Oxidation of Aryl Sulfides to Sulfones with Alumina-Supported Ruthenium Catalyst in Dimethyl Carbonate–Water Media

Abstract

A new procedure for the oxidation of sulfides to sulfones utilizing heterogeneous ruthenium reagent has been developed. A small amount of ruthenium trichloride (RuCl 3) supported on alumina and excess sodium metaperiodate (NaIO 4) was used to produce the ruthenium oxidizing catalyst in the reaction mixture. Sodium metaperiodate oxidized the pre-catalyst RuCl 3 to RuO 4 and also maintained a constant supply of RuO 4 by oxidizing lower valent ruthenium ions during the course of the reaction. An environmentally friendly solvent mixture of dimethyl carbonate (DMC) and water was employed. A wide variety of aromatic sulfides were oxidized to sulfones in good to excellent yields by utilizing this procedure.

A Green Method for the Synthesis of Sulfones from Thioethers

“…仪器与试剂 熔点由 SGW X-4A 显微熔点仪测定 1. H NMR (400 MHz)和13 C NMR (100 MHz)数据皆是用 Bruker Avance 400 型核磁共振仪测试所得, 所用溶剂均为 CDCl 3 . 高 分辨质谱数据由 Waters-GCT 质谱仪测定.…”