Oxidative chlorination of [U-14C] phenol

Abstract

SUMMARYThe preparation of [U-14C] 2,4-dichlorophenol was formerly achieved by a Sandmeyer reaction with p-'4C] 2,4-dichloroaniline but this sensitive step gave unreproductive yields in our hands.We describe another route to [U-I4C] 2,4-dichlorophenol by the oxidative chlorination of !J.J-I4C] phenol. This shorter route is safer and gives satisfactory yields. The nature of the oxidizer is discussed.

Oxidation of Pollutants Catalyzed by Metallophthalocyanines

“…6 The specific activity of labeled TCP was 62 mCi/ mmol with a radiochemical purity of 98.5%. 59 The catalytic oxidation of (U-14 C)-TCP by FePcS/H 2 O 2 was performed with 0.074 and 10 mol equiv of FePcS and H 2 O 2 versus TCP, respectively, at room temperature, and products were analyzed after 90 min of reaction. Eleven percent of the initial radioactivity was recovered as CO 2 .…”

“…Consequently, to avoid any possible artifact, we decided to investigate the formation of CO 2 from TCP by monitoring the release of labeled CO 2 during the oxidation of a (U- 14 C)-TCP by FePcS/H 2 O 2 to have a complete material balance of oxidation products . The specific activity of labeled TCP was 62 mCi/mmol with a radiochemical purity of 98.5% …”