Oxidative cleavage of alkynes: a review of the methods invented so far and their application possibilities in green organic synthesis

Abstract

Oxidative cleavage products of alkynes are used just as frequently in preparative organic synthesis as in industry. Compared to the number of methods for the oxidative cleavage of olefins, fewer methods for the oxidative cleavage of alkynes have been described, and most of these have only been tested on selected substrates. It is assumed that chemists avoid direct oxidative cleavage reactions of alkynes in their planning and instead prefer to use the corresponding oxidized olefin product for oxidative cleavage. In the review, the oxidative cleavage methods invented so far are presented in the literature. Among them are ozonolysis, transition metal-catalyzed oxidative cleavage methods, oxidative cleavages using main-group elements and lanthanide catalyzed oxidative cleavage methode.