Oxidative coupling of primary amines to imines catalyzed by CoCl₂·6H₂O

Abstract

A high-performance, readily available and eco-friendly cobalt catalyst has been suggested for the first time for the additive-free oxidative coupling of primary amines to imines. Different substituted benzylamine and heteroaryl methanamine compounds could be transformed into their corresponding imines in good to excellent yields over this catalyst. Meanwhile, it has been demonstrated that this catalyst can also afford the oxidative coupling of various benzylamines with o-phenylenediamine to produce benzimidazole derivatives in medium to good yields.

Thiophene-Based Covalent Triazine Frameworks as Visible-Light-Driven Heterogeneous Photocatalysts for the Oxidative Coupling of Amines

“…However, most of the current available methods rely on the catalytic activity of rare metal catalysts, such as Co, Ru, Mn, etc. [40]. For this reason, new sustainable strategies for imine production, such as the oxidative coupling of amines [41,42], provide an attractive alternative to the traditional synthetic methods that require an acid catalyst and produce large amounts of chemical wastes.…”