2004
DOI: 10.1016/j.clinbiochem.2004.01.002
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Oxidative state in intestine and liver after partial hepatectomy in rats. Effect of bombesin and neurotensin

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Cited by 38 publications
(28 citation statements)
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“…These situations interfere with the normal regenerative pathways or initiate apoptotic pathways, resulting in a net loss of functional hepatocytes (16). Increased oxidative stress during the early phase of liver regeneration had been observed as a cause of surgery and a reactive response of the reduced organ to compensate for the extra functional load (17)(18)(19). We observed significantly increased oxidative stress and liver function tests levels and significantly decreased liver tissue GSH levels after partial hepatectomy.…”
Section: Discussionmentioning
confidence: 51%
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“…These situations interfere with the normal regenerative pathways or initiate apoptotic pathways, resulting in a net loss of functional hepatocytes (16). Increased oxidative stress during the early phase of liver regeneration had been observed as a cause of surgery and a reactive response of the reduced organ to compensate for the extra functional load (17)(18)(19). We observed significantly increased oxidative stress and liver function tests levels and significantly decreased liver tissue GSH levels after partial hepatectomy.…”
Section: Discussionmentioning
confidence: 51%
“…Hepatic lipid peroxidation peaks at 24 hours after partial hepatectomy when GSH content is minimum (19,20). It has also been addressed that oxidative stress is reduced before cell division (19,21,25). Increased oxidative stress could diminish the regeneration process.…”
Section: Discussionmentioning
confidence: 99%
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“…Hepatic lipid peroxidation peaks at 24 h after PH when GSH content is minimum [1,14,16]. It has also been addressed that oxidative stress is reduced before cell division [2,6,46]. Increased oxidative stress could diminish the regeneration process.…”
Section: A B Cmentioning
confidence: 99%
“…The role of the antioxidant defence system, which includes SOD and GSH, is well characterised in the liver [28]. Increased oxidative stress during the early phase of liver regeneration had been observed as a cause of surgery and a reactive response of the reduced organ to compensate for the extra functional load [2,5,13]. Hepatic lipid peroxidation peaks at 24 h after PH when GSH content is minimum [1,14,16].…”
Section: A B Cmentioning
confidence: 99%