2009
DOI: 10.1016/j.ejogrb.2009.02.018
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Oxidative stress and epididymal sperm transport, motility and morphological defects

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Cited by 64 publications
(48 citation statements)
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References 28 publications
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“…In addition, no correlation was found between endogenous or supplemented ascorbate and motility preservation through the freezing process. However, we did verify that oxidative stress is negatively correlated with initial motility, in agreement with earlier reports (8,(34)(35)(36)(37)(38)(39). One possible mechanism for the improved preservation with AA2G may be directly related to the recycling process of ascorbate.…”
Section: Discussionsupporting
confidence: 92%
“…In addition, no correlation was found between endogenous or supplemented ascorbate and motility preservation through the freezing process. However, we did verify that oxidative stress is negatively correlated with initial motility, in agreement with earlier reports (8,(34)(35)(36)(37)(38)(39). One possible mechanism for the improved preservation with AA2G may be directly related to the recycling process of ascorbate.…”
Section: Discussionsupporting
confidence: 92%
“…1). Recent studies have indicated that increased ROS levels may be a major cause of idiopathic male infertility [74,75]. Increased ROS production is inversely correlated with sperm function [76].…”
Section: Free Radical Theory Of Aging and Apoptosismentioning
confidence: 99%
“…Morte et al (2008) evidenciaron una correlación positiva entre los niveles de oxidación de lípidos y proteínas en los espermatozoides y en el plasma seminal, con la presencia de defectos severos en la función de los espermatozoides de equinos subfértiles, indicando que la oxidación de lípidos y proteínas podría ser útil para la identificación de machos con problemas de fertilidad. Para la especie humana, se ha evidenciado un incremento significativo en el nivel de grupos carbonilos, generados como consecuencia de la oxidación proteica, en el semen de pacientes oligoastenoteratozoospérmicos en comparación con pacientes fértiles (p<0.001); asimismo, altos niveles de grupos carbonilos se han correlacionado positivamente con anormalidades del axonema del espermatozoide, con una consecuente disminución de su movilidad progresiva (Moustafa et al, 2009). …”
Section: Resultados Y Discusiónunclassified