2020
DOI: 10.21203/rs.3.rs-37984/v1
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Oxidized Low-Density Lipoprotein (Ox-LDL) and Malondialdehyde (MDA) and Menopause: Loss of Protective Effect of Premenopuasl Status in Type 2 Diabetes Mellitus

Abstract: Background: A network of factors suggested to influence oxidative modification of serum low-density lipoprotein (ox-LDL) concentrations and it plays critical role in diabetic copmlications.This study aimed to assess the joint effect of Type 2 diabetes mellitus (T2DM), gender and menopausal status on ox-LDL and Malondialdehyde (MDA) levels.Material and Method: A total of 594 female and male participants were divided into six groups: 189 postmenopausal women with T2DM, 79 premenopausal women with T2DM, 54 premen… Show more

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“…Oxidized low-density lipoprotein (Ox-LDL) is formed in the oxidation state of low-density lipoprotein cholesterol (LDL-C) which then leads to the accumulation of foamy cells under the endothelium. And these foam cells in the development of atherosclerotic plaques [21].…”
Section: Discussionmentioning
confidence: 99%
“…Oxidized low-density lipoprotein (Ox-LDL) is formed in the oxidation state of low-density lipoprotein cholesterol (LDL-C) which then leads to the accumulation of foamy cells under the endothelium. And these foam cells in the development of atherosclerotic plaques [21].…”
Section: Discussionmentioning
confidence: 99%