Oxidized sodium alginate cross-linked calcium alginate/antarctic krill protein composite fiber for improving strength and water resistance

Li, Zheng; Guo, Jing; Guan, Fang; Yin, Juhui; Yang, Qiang; Zhang, Sen; Tian, Jun; Zhang, YiHang; Ding, MingFei; Wen-ming, Wang

doi:10.1016/j.colsurfa.2022.130317

Cited by 31 publications

(9 citation statements)

References 33 publications

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“…These disadvantages were overcome by the use of ADA. In addition, the disadvantages of traditional aldehyde cross-linking agents such as high toxicity and ease of precipitation were also avoided [ 56 ]. High-molecular-weight alginate hardly degrades in the human body because of the lack of alginate-degrading enzymes, while alginate with a molecular weight lower than 50 kDa can be removed from the body through kidney excretion mechanisms.…”

Section: Resultsmentioning

confidence: 99%

Cross-Linked Alginate Dialdehyde/Chitosan Hydrogel Encompassing Curcumin-Loaded Bilosomes for Enhanced Wound Healing Activity

Sideek,

El-Nassan,

Fares

et al. 2024

Pharmaceutics

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The current study aimed to fabricate curcumin-loaded bilosomal hydrogel for topical wound healing purposes, hence alleviating the poor aqueous solubility and low oral bioavailability of curcumin. Bilosomes were fabricated via the thin film hydration technique using cholesterol, Span® 60, and two different types of bile salts (sodium deoxycholate or sodium cholate). Bilosomes were verified for their particle size (PS), polydispersity index (PDI), zeta potential (ZP), entrapment efficiency (EE%), and in vitro drug release besides their morphological features. The optimum formulation was composed of cholesterol/Span® 60 (molar ratio 1:10 w/w) and 5 mg of sodium deoxycholate. This optimum formulation was composed of a PS of 246.25 ± 11.85 nm, PDI of 0.339 ± 0.030, ZP of −36.75 ± 0.14 mv, EE% of 93.32% ± 0.40, and the highest percent of drug released over three days (96.23% ± 0.02). The optimum bilosomal formulation was loaded into alginate dialdehyde/chitosan hydrogel cross-linked with calcium chloride. The loaded hydrogel was tested for its water uptake capacity, in vitro drug release, and in vivo studies on male Albino rats. The results showed that the loaded hydrogel possessed a high-water uptake percent at the four-week time point (729.50% ± 43.13) before it started to disintegrate gradually; in addition, it showed sustained drug release for five days (≈100%). In vivo animal testing and histopathological studies supported the superiority of the curcumin-loaded bilosomal hydrogel in wound healing compared to the curcumin dispersion and plain hydrogel, where there was a complete wound closure attained after the three-week period with a proper healing mechanism. Finally, it was concluded that curcumin-loaded bilosomal hydrogel offered a robust, efficient, and user-friendly dosage form for wound healing.

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Section: Resultsmentioning

confidence: 99%

Cross-Linked Alginate Dialdehyde/Chitosan Hydrogel Encompassing Curcumin-Loaded Bilosomes for Enhanced Wound Healing Activity

Sideek,

El-Nassan,

Fares

et al. 2024

Pharmaceutics

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“…The data were based on the reported literature of high-performance fibers based on alginate fibers, cellulose fibers, and silk fibers. hydroxyapatite/alginate fibers, sodium polyacrylate/alginate fibers, Ag Nanowires/silkworm silk fibers, oxidized SA/calcium alginate/antarctic krill protein composite fibers; CNFs/RSP fibers, regenerated silk fibers, bacteria nanofibers/alginate fibers, reinforced silkworm fibers, and other reinforced fibers. ,, …”

Section: Resultsmentioning

confidence: 99%

“…Comparing the mechanical properties of reported biomass based fibers (Table S7), including hydroxyapatite/alginate fibers, sodium polyacrylate/alginate fibers, Ag Nanowires/silkworm silk fibers, oxidized SA/calcium alginate/antarctic krill protein composite fibers; cellulose nanofibrils (CNFs)/recombinant spider silk proteins(RSP) fibers, regenerated silk fibers, bacteria nanofibers/alginate fibers, reinforced silkworm fibers, and other fibers, ,, some of them exhibited negative increment in elongation with a limited increment in strength (Figure i). The others were either high strength increments or low elongation increments or vice versa, leading to insufficient enhancement in toughness (Figure j).…”

Section: Resultsmentioning

confidence: 99%

Self-Assembly Reinforced Alginate Fibers for Enhanced Strength, Toughness, and Bone Regeneration

Cui,

Liu,

Xie

et al. 2024

Biomacromolecules

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Material reinforcement commonly exists in a contradiction between strength and toughness enhancement. Herein, a reinforced strategy through self-assembly is proposed for alginate fibers. Sodium alginate (SA) microstructures with regulated secondary structures are assembled in acidic and ethanol as reinforcing units for alginate fibers. Acidity increases the flexibility of the helix and contributes to enhanced extendibility. Ethanol is responsible for formation of a stiff β-sheet, which enhances the modulus and strength. The structurally engineered SA assembly exhibits robust mechanical compatibility, and thus reinforced alginate fibers possess an improved tensile strength of 2.1 times, a prolonged elongation of 1.5 times, and an enhanced toughness of 3.0 times compared with SA fibers without reinforcement. The reinforcement through self-assembly provides an understanding of strengthening and toughening mechanism based on secondary structures. Due to a similar modulus with bones, reinforced alginate fibers exhibit good efficacy in accelerating bone regeneration in vivo.

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“…As such, it is crucial to carefully selec immobilization method to ensure that the microorganisms can maintain their functio ity effectively [98][99][100]. The selection of a method depends on the specific needs o process, the characteristics of the microorganisms, and the environmental conditions Immobilization methods are classified as either physical or chemical, both offering spe advantages [101].…”

Section: Immobilization Methodsmentioning

confidence: 99%

“…The selection of a method depends on the specific needs of the process, the characteristics of the microorganisms, and the environmental conditions [ 19 ]. Immobilization methods are classified as either physical or chemical, both offering specific advantages [ 101 ].…”

Section: Immobilization Methodsmentioning

confidence: 99%

A Review of the Strategic Use of Sodium Alginate Polymer in the Immobilization of Microorganisms for Water Recycling

Bustos-Terrones

2024

Polymers

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In the quest for advanced and environmentally friendly solutions to address challenges in the field of wastewater treatment, the use of polymers such as sodium alginate (Na-Alg) in combination with immobilized microorganisms (IMs) stands out as a promising strategy. This study assesses the potential of Na-Alg in immobilizing microorganisms for wastewater treatment, emphasizing its effectiveness and relevance in environmental preservation through the use of IMs. Advances in IMs are examined, and the interactions between these microorganisms and Na-Alg as the immobilization support are highlighted. Additionally, models for studying the kinetic degradation of contaminants and the importance of oxygen supply to IMs are detailed. The combination of Na-Alg with IMs shows promise in the context of improving water quality, preserving ecological balance, and addressing climate change, but further research is required to overcome the identified challenges. Additional areas to explore are discussed, which are expected to contribute to the innovation of relevant systems.

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Oxidized sodium alginate cross-linked calcium alginate/antarctic krill protein composite fiber for improving strength and water resistance

Cited by 31 publications

References 33 publications

Cross-Linked Alginate Dialdehyde/Chitosan Hydrogel Encompassing Curcumin-Loaded Bilosomes for Enhanced Wound Healing Activity

Cross-Linked Alginate Dialdehyde/Chitosan Hydrogel Encompassing Curcumin-Loaded Bilosomes for Enhanced Wound Healing Activity

Self-Assembly Reinforced Alginate Fibers for Enhanced Strength, Toughness, and Bone Regeneration

A Review of the Strategic Use of Sodium Alginate Polymer in the Immobilization of Microorganisms for Water Recycling

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