Oxime Based Selective Fluorescent Sensor for Arsenate Ion in a Greener Way with Bio-Imaging Application

Abstract

A newly designed oxime based probe, 2,4-dihydroxyacetophenone-oxime (DHAO), was found to recognize H2AsO4 Keywords Oxime-imine based turn-on fluorescent sensor, selective detection of arsenate ion, DFT calculations, intracellular imaging

A review on oxime functionality: an ordinary functional group with significant impacts in supramolecular chemistry

“…A 2,4-dihydroxyacetophenone based oxime functionalised probe Oxm-111 was designed and synthesised for selective and sensitive detection of arsenate ion in HEPES buffer at pH = 7.2. 166 Oxm-111 exhibits two absorption peaks at 265 nm and 300 nm. However, when arsenate was present, the absorption peak at 300 nm gradually migrated to 330 nm, while diminishing absorption was noted at 265 nm.…”

Colorimetric differentiation of arsenite and arsenate anions using a bithiophene sensor with two binding sites: DFT studies and application in food and water samples

“…15,22,[37][38][39][40][41][42][43] Most chemosensors for arsenic anions operate through uorogenic methods, requiring uorescence lamps and instruments for visualizing the detection process. 6,36,42,[44][45][46][47][48][49][50] Colorimetric detection, on the other hand, offers the advantage of naked-eye visualization and identication of detection phenomena. However, colorimetric sensors reported for arsenic anions have limitations, including interference by other anions, inability to sense in aqueous/semiaqueous media, poor color changes, and the need to improve detection limits and binding constants.…”

ZnAl2O4 Nanomaterial as a Naked-Eye Arsenate Sensor: A Combined Experimental and Computational Mechanistic Approach

“…Therefore, the development of safe and benign methods for the real-time identification and quantification in the ppb level of such a toxicant in water has become a very crucial task demanding contemporary research. Several chemical-based analytical methods have been employed for the trace-level identification of arsenate, for example, inductively coupled plasma atomic emission spectrometry (ICP-AES), capillary electrophoresis inductively coupled plasma mass spectrometry (CE-ICP-MS), − neutron activation analysis (NAA), atomic absorption spectrometry (AAS), , hydride generation atomic fluorescence spectrometry (HG-AFS), HPLC, and cathodic stripping voltammetry, and anodic stripping voltammetry (CSV and ASV). − However, these techniques are costly, time-consuming, or necessitate complicated working procedures and arduous sample preparation. Sensing methods have already become the greatest way of analysis due to them being less expensive, nondestructive, simple processes, capable of naked-eye monitoring, rapid analysis, having a low limit of detection (LOD), and good selectivity. − …”