Oxygen cost of walking, physical activity, and sedentary behaviours in rheumatoid arthritis

Paul, Lorna; Rafferty, Daniel; Marshall-McKenna, Rebecca; Gill, Jason M.R.; McInnes, Iain B.; Porter, Duncan; Woodburn, James

doi:10.3109/03009742.2013.802009

Cited by 22 publications

(22 citation statements)

References 36 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…However, when controlled for potential explanatory variables, only reduced activity due to fatigue, physical fatigue and disease activity were found to be statistically significantly lower in patients being regularly physically active. Findings from this study support previous studies documenting low levels of physical activity and increased sitting time in patients with RA compared to controls [9,[28][29][30]. Although no direct comparison was made in the present study, we found that 27 % of the patients in our study reported being primarily sedentary compared to 16.4 % of the Danish general population [31].…”

Section: Discussionsupporting

confidence: 92%

Physical activity and the association with fatigue and sleep in Danish patients with rheumatoid arthritis

et al. 2015

View full text Add to dashboard Cite

The aim of this study was to examine physical activity behavior in patients with rheumatoid arthritis and to identify potential correlates of regular physical activity including fatigue, sleep, pain, physical function and disease activity. A total of 443 patients were recruited from a rheumatology outpatient clinic and included in this cross-sectional study. Physical activity was assessed by a four-class questionnaire, in addition to the Physical Activity Scale. Other instruments included the Multidimensional Fatigue Inventory (MFI), the Pittsburgh Sleep Quality Index and the Health Assessment Questionnaire. Disease activity was obtained from a nationwide clinical database. Of the included patients, 80 % were female and mean age was 60 (range 21-88 years). Hereof, 22 % (n = 96) were regularly physically active, and 78 % (n = 349) were mainly sedentary or having a low level of physical activity. An inverse univariate association was found between moderate to vigorous physical activity, and fatigue (MFI mental, MFI activity, MFI physical and MFI general), sleep, diabetes, depression, pain, patient global assessment, HAQ and disease activity. The multivariate prediction model demonstrated that fatigue-related reduced activity and physical fatigue were selected in >95 % of the bootstrap samples with median odds ratio 0.89 (2.5-97.5 % quantiles: 0.78-1.00) and 0.91 (2.5-97.5 % quantiles: 0.81-0.97), respectively, while disease activity was selected in 82 % of the bootstrap samples with median odds ratio 0.90. Moderate to vigorous physical activity in patients with rheumatoid arthritis is associated with the absence of several RA-related factors with the most important correlates being reduced activity due to fatigue, physical fatigue and disease activity.

show abstract

Section: Discussionsupporting

confidence: 92%

Physical activity and the association with fatigue and sleep in Danish patients with rheumatoid arthritis

et al. 2015

View full text Add to dashboard Cite

show abstract

“…It is possible that some minutes are classified as 'no walking registered', by which the person was standing upright, or possibly making weight shifts and taking small steps that were unregistered by the SAM. It was shown previously by Paul et al [42] that these periods of incidental movement could account for up to four hours per day. Questionnaires such as the International PA questionnaires could be applied for this reason, however, have the drawback of potentially impaired recall to accurately quantify PA.…”

Section: Discussionmentioning

confidence: 82%

Understanding walking activity in multiple sclerosis: step count, walking intensity and uninterrupted walking activity duration related to degree of disability

et al. 2016

View full text Add to dashboard Cite

In multiple sclerosis (MS), physical activity (PA) is most commonly measured as number of steps, while also walking intensity and walking activity duration are keys for a healthy lifestyle. The aim of this study was to investigate (1) the number of steps persons with MS (PwMS) take; (2) the number of steps they take at low and moderate intensity; and (3) their walking activity duration for 2, 3, 6, 10, 12 and 14 uninterrupted minutes; all related to the degree of disability. 64 PwMS participated, distinguished in a mild (n = 31) and moderate MS subgroup (n = 34) based on their ambulatory dysfunction (Disease Steps). Standardized clinical tests were performed, and step data from the StepWatch Activity Monitor were collected for seven consecutive days. The results showed that (1) step count in PwMS was lower than PA recommendations, and is negatively influenced by a higher disability degree. (2) No walking was registered during 77 % of the day. PwMS are making steps for 22 % at low and only 1 % at moderate intensity. (3) Both MS subgroups rarely walk for more than six uninterrupted minutes, especially not at moderate intensity. PwMS need to be encouraged to make steps at moderate intensity, and to make steps for longer periods of time (minimal ten uninterrupted minutes).

show abstract

“…Joint disease in rheumatoid arthritis (RA) often limits participation in moderate and vigorous physical activities. Individuals with RA generally tend to be sedentary, as a result of polyarticular pain, stiffness, fatigue, and functional limitations (2)(3)(4). In a cross-sectional study of patients with RA from 21 countries, approximately 71% reported being sedentary and not engaging in regular physical activity (2).…”

Section: Introductionmentioning

confidence: 99%

“…Individuals with RA generally tend to be sedentary as a result of poly-articular pain, stiffness, fatigue, and functional limitations (2–4). In a cross-sectional study of patients with RA from 21 countries, around 71% reported being sedentary and not engaging in regular physical activity (2) While a physically active lifestyle in RA is important to decrease the risk of cardiovascular disease, (5) it might be unreasonable to expect that all individuals with RA can shift from their habitual sedentary behavior to regular participation in PA at moderate or higher intensity.…”

mentioning

confidence: 99%

Association of Light‐Intensity Physical Activity With Lower Cardiovascular Disease Risk Burden in Rheumatoid Arthritis

Khoja

Almeida

Wasko

et al. 2016

Arthritis Care & Research

View full text Add to dashboard Cite

Objective: To characterize physical activity (PA) in individuals with rheumatoid arthritis (RA) and determine the associations between PA participation in light to moderate intensities and cardiovascular risk factors, disability, and disease activity. Methods: Cross-sectional study using data from two RA cohorts. PA was measured using an accelerometry-based activity monitor, and characterized as minutes/day in sedentary (≤1 metabolic equivalent-MET), very light (1.1–1.9 METs), light (2–2.9 METs), and moderate activities (≥3 METs). Cardiovascular markers included body mass index, blood pressure, insulin resistance, and lipid profile. Disability and disease activity were measured with the Health Assessment Questionnaire (HAQ) and Disease Activity Score-28 (DAS-28), respectively. Associations between PA at each intensity and health-markers were assessed by multiple linear regression models adjusted by age, sex, and cohort. Results: Ninety-eight subjects (58 ± 9 years, 85% female) were included. Subjects spent 9.8 hours/day being sedentary, 3.5 hours/day in very light PA, 2.1 hours/day in light PA and 35 minutes/day in moderate PA. Only 17% were physically active (≥150 minutes/week of moderate PA in 10-minute bouts). Regression models showed that very light, light and moderate PA were inversely associated with most cardiovascular risk factors, the HAQ, and DAS-28 scores (R2Δrange: .04 to .52, p <.05). The associations between PA and cardiovascular markers were either equivalent or stronger at very light- and light-intensities as compared to moderate-intensity. Conclusions: Individuals with RA are mostly active at very light and light intensities. PA at these intensities associate favorably with cardiovascular markers, and lower disability and disease activity in RA.

show abstract

Oxygen cost of walking, physical activity, and sedentary behaviours in rheumatoid arthritis

Cited by 22 publications

References 36 publications

Physical activity and the association with fatigue and sleep in Danish patients with rheumatoid arthritis

Physical activity and the association with fatigue and sleep in Danish patients with rheumatoid arthritis

Understanding walking activity in multiple sclerosis: step count, walking intensity and uninterrupted walking activity duration related to degree of disability

Association of Light‐Intensity Physical Activity With Lower Cardiovascular Disease Risk Burden in Rheumatoid Arthritis

Contact Info

Product

Resources

About