Oxygen-Enhanced MRI of the Lungs: Intraindividual Comparison Between 1.5 and 3 Tesla

Abstract

Oxygen-enhanced pulmonary MRI is feasible at 3 Tesla. However, signal enhancement is currently more heterogeneous and slightly lower at 3 T.

Clinical use of oxygen‐enhanced T1 mapping MRI of the lung: Reproducibility and impact of closed versus loose fit oxygen delivery system

“…The T 1 relaxation times obtained for this group of healthy volunteers correspond to previously published data, which showed values between 1200 and 1300 msec .…”

Pediatric whole-body magnetic resonance imaging: Intra-individual comparison of technical quality, artifacts, and fixed structure visibility at 1.5 and 3 T

“…[ 1 2 3 4 5 6 7 8 ] WBMRI can be performed at both 1.5 and 3 T magnetic field strengths. There are a few studies comparing these two field strengths in adults for whole-body MR angiography,[ 9 ] oxygen-enhanced MRI of lungs,[ 10 ] cardiac and coronary imaging,[ 11 12 ] and abdominal diffusion-weighted imaging (DWI). [ 13 ] Comparison of image quality and artifacts of WBMRI performed at 1.5 and 3 T has also been performed in adults.…”

3D Oxygen‐Enhanced MRI at 3T MR System: Comparison With Thin‐Section CT of Quantitative Capability for Pulmonary Functional Loss Assessment and Clinical Stage Classification of COPD in Smokers

“…As an alternative to hyperpolarized gas MRI, oxygen‐enhanced (O 2 ‐enhanced) MRI has been suggested as having the potential for evaluating not only ventilation, but also oxygen diffusion from alveoli to capillary bed in patients with COPD, lung cancer, interstitial lung disease, and asthma since the mid‐1990s 13‐27 . In comparison with hyperpolarized gas MRI and fluorine MRI, this technique has several advantages: 1) proton‐based MRI performed with a clinical scanner without any specific modification; 2) no need for special equipment such as polarizers and specialized transmitter and receiver coils; 3) the naturally abundant and the most widely available physiological gas; and 4) easier oxygen delivery using oxygen piping in the MR examination room and clinically available ventilation masks.…”

“…In comparison with hyperpolarized gas MRI and fluorine MRI, this technique has several advantages: 1) proton‐based MRI performed with a clinical scanner without any specific modification; 2) no need for special equipment such as polarizers and specialized transmitter and receiver coils; 3) the naturally abundant and the most widely available physiological gas; and 4) easier oxygen delivery using oxygen piping in the MR examination room and clinically available ventilation masks. However, O 2 ‐enhanced MRI also has a few drawbacks: 1) limited coverage of the entire lung due to 2D acquisition; 2) use of a 1.5T MR system due to the limited specific absorption rate (SAR); and 3) semiquantitative assessment of oxygen enhancement 13‐27 . Therefore, efforts have been made to develop a new oxygen‐enhanced MR sequence to help overcome these drawbacks 17,18,22,27 .…”

“…However, O 2 ‐enhanced MRI also has a few drawbacks: 1) limited coverage of the entire lung due to 2D acquisition; 2) use of a 1.5T MR system due to the limited specific absorption rate (SAR); and 3) semiquantitative assessment of oxygen enhancement 13‐27 . Therefore, efforts have been made to develop a new oxygen‐enhanced MR sequence to help overcome these drawbacks 17,18,22,27 . In addition, clinical installation of a 3T MR system has increased all over the world.…”