Oxygen mass transfer and oxygen respiration rate measurements utilizing fast response oxygen electrodes

Heineken, F. G.

doi:10.1002/bit.260130502

Cited by 42 publications

(5 citation statements)

References 10 publications

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“…The volumetric oxygen transport coefficient (kLa) in the fermentation broth and the specific respiration rate (Qo2 X) were determined by the dynamic method (Heineken 1971 ;Bandyopadyay and Humphrey 1967).…”

Section: Methodsmentioning

confidence: 99%

Submerged citric acid fermentation: rheological properties ofAspergillus niger broth in a stirred tank reactor

Berovič¹,

Cimerman²,

Steiner

et al. 1991

Appl Microbiol Biotechnol

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A large number of submerged citric acid fermentations in a beet molasses substrate was studied.The development of Aspergillus niger from conidia to pellets was followed. Rheological characteristics of the fermentation broth including the pellets were determined. The results obtained confirm the fact that the non-Newtonian pseudoplastic behaviour of the fermentation broth was due to the presence of mycelial pellets. The most significant changes in rheological properties occurred during the period of maximal citric acid production and increase in biomass.

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Section: Methodsmentioning

confidence: 99%

Submerged citric acid fermentation: rheological properties ofAspergillus niger broth in a stirred tank reactor

Berovič¹,

Cimerman²,

Steiner

et al. 1991

Appl Microbiol Biotechnol

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“…In practice, this is seldom the case, and therefore many models have been designed to calculate kLA from the probe response all the same. These range from one for first order response (Van de Sande, 1974) to 0019-7882/79/1118-0357$01.00/0 © 1979 American Chemical Society complicated models for diffusion (Heineken, 1970(Heineken, , 1971; Linek, 1972, andLinek et al, 1973).…”

Section: Introductionmentioning

confidence: 99%

Review of Measuring Methods and Results in Nonviscous Gas-Liquid Mass Transfer in Stirred Vessels

Riet¹

1979

Ind. Eng. Chem. Proc. Des. Dev.

664

310

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“…After the startup period has elapsed, i.e., when the steady-state holdup has been attained, the differential balances describing oxygen concentration changes in the system become identical with eqs. (14)- (17). Various alternatives of gas interchange were applied in the study, namely, N2 + 0 2 , 0, + N2, air + N2, and N2 -+ air.…”

Section: Methods For Determining Kiamentioning

confidence: 99%

Use of glucose oxidase system in measuring aeration capacity of fermentors. Comparison of the dynamic and steady‐state methods of k_la measurement

Linek

Beneš

Hovorka

et al. 1981

Biotech & Bioengineering

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SummaryA steady-state method for kla determination has been presented using the Michaelis-Menten two-substrate kinetic equation for oxidation of glucose in the presence of the enzymes glucose oxidase and excess catalase. The conditions have been specified where spontaneous hydrolysis of lactone is sufficiently rapid, thus eliminating inhibitory action of lactone on the oxidation. In glucose oxidase-free batches, the kla values were determined using various modifications of the dynamic method. The dynamic methods in which gas interchange was effected without interrupting aeration and agitation of the batch yielded erroneously lower kla values as compared to the results of steady-state methods if the measured kla value was higher than 0.03 s-I . The values yielded by the dynamic method in which the gas interchange was effected at the same time with turning on aeration and agitation of the batch agreed with values resulting from the steady-state method provided that the measured kla values were lower than 0.08 s -' and the simultaneous interfacial transport of nitrogen and oxygen had been taken into account in the evaluation. At k,a values higher than 0.08 s -' , this modification of the dynamic method also yielded lower kla values as compared with the outcome of the steady-state method. The experiments performed do not, however, allow one to decide unambiguously on whether these lower kta values are due to failure of the adopted model to describe adequately the dynamic behavior of the system or whether they are true values differing from those yielded by the steady-state method on account of different physical properties of compared batches.

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Oxygen mass transfer and oxygen respiration rate measurements utilizing fast response oxygen electrodes

Cited by 42 publications

References 10 publications

Submerged citric acid fermentation: rheological properties ofAspergillus niger broth in a stirred tank reactor

Submerged citric acid fermentation: rheological properties ofAspergillus niger broth in a stirred tank reactor

Review of Measuring Methods and Results in Nonviscous Gas-Liquid Mass Transfer in Stirred Vessels

Use of glucose oxidase system in measuring aeration capacity of fermentors. Comparison of the dynamic and steady‐state methods of k_la measurement

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Oxygen mass transfer and oxygen respiration rate measurements utilizing fast response oxygen electrodes

Cited by 42 publications

References 10 publications

Submerged citric acid fermentation: rheological properties ofAspergillus niger broth in a stirred tank reactor

Submerged citric acid fermentation: rheological properties ofAspergillus niger broth in a stirred tank reactor

Review of Measuring Methods and Results in Nonviscous Gas-Liquid Mass Transfer in Stirred Vessels

Use of glucose oxidase system in measuring aeration capacity of fermentors. Comparison of the dynamic and steady‐state methods of kla measurement

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Use of glucose oxidase system in measuring aeration capacity of fermentors. Comparison of the dynamic and steady‐state methods of k_la measurement