Oxygen-ozone therapy for musculoskeletal pain in rehabilitation: Evidence and future perspectives

Abstract

Dear colleagues,Musculoskeletal pain is a common issue in several pathological conditions like osteoarthritis and low back pain, with relevant negative implications in terms of chronic pain development, disability and increased sanitary costs worldwide [?]. As the search for minimally invasive treatment options intensifies, oxygen-ozone therapy has emerged as a promising intervention and its anti-inflammatory and tissue-regenerative properties makes it as a viable alternative to more conventional treatments like corticosteroid injections [?,?].This editorial focusses on the current evidence supporting oxygen-ozone therapy, in particular in osteoarthritis and low back pain treatment, and explores its potential integration with other therapeutic strategies like physical rehabilitation interventions.Recent studies highlighted the role of oxygen-ozone therapy in the management of knee [?