Oxygen Saturation Targeting by Automatic Control of Inspired Oxygen in Premature Infants

Claure, Nelson; Bancalari, Eduardo

doi:10.1542/neo.16-7-e406

Cited by 5 publications

(3 citation statements)

References 40 publications

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“…The previous studies have shown some risks related to development of mechanized control systems in oxygen therapy for respiratory complicated patients (1,3,5). Therefore, a system was designed and implemented that could easily and promptly warn nurses based on patients' condition.…”

Section: Strengths Of Studymentioning

confidence: 99%

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Remote Closed-Loop Automatic Oxygen Control in Preterm Infants

Moradi

Kalhori

Saeedi

et al. 2019

Preprint

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Background Different automated systems have been developed to improve maintenance of target range of arterial oxygen saturation (SPO2) in premature infants with respiratory distress. This study aimed to develop a Remote Closed-Loop Automatic Oxygen Control (RCLAC) as an efficient monitoring device. Then the mean of fraction of inspired oxygen (FIO2) and SPO2 by routine manual control (RMC) and RCLAC were compared.Methods A developmental-descriptive study was carried out in an Iranian hospital (Tehran-Iran; 2015-2017). Eighteen preterm infants with gestational age 24-28 weeks entered the study. A database was prepared based on pulse oximeter parameters. A Wi-Fi module was implemented to receive data from pulse oximeter and send inputs to user's mobile. Vibrate alarm was implemented for high or low FIO2. After receiving notifications associated with increase or decrease of FIO2 levels and user's confirmation; the alterations were applied on the ventilator.Results The mean FIO2 in RMC system was significantly higher than RCLAC system (98.1± 2.67 vs. 79.5±16.03; p = 0.0001). According to the results, when the SPO2 reached close to target SPO2 range and consequently FIO2 changed (decreased or increased based on target SPO2), heart rate showed a regular beating with decrease in the numbers.Conclusion Remote Closed-Loop Automatic Oxygen Control system as a simple device could prevent preterm neonates from sustained hypo-hyperoxemic and arrhythmia episodes. Moreover by using RCLAC, there was no need for continuous monitoring that may reduce workload of NICUs medical staff. Collecting reliable data and recording information in digital forms were also other benefits.

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Section: Strengths Of Studymentioning

confidence: 99%

“…On the other hand, hyperoxemia in some cases may lead heart, lungs, brain, retina and hearing system damages. Maintenance of adequate blood oxygen concentration to minimize the risks of both hypoxemia and hyperoxemia are the main goal related mechanical ventilation in hospitalized premature infants (1)(2)(3)(4).…”

Section: Introductionmentioning

confidence: 99%

Remote Closed-Loop Automatic Oxygen Control in Preterm Infants

Moradi

Kalhori

Saeedi

et al. 2019

Preprint

View full text Add to dashboard Cite

show abstract

“…On the other hand, hyperoxemia in some cases may lead to heart, lungs, brain, retina and hearing system damages. Maintenance of adequate blood oxygen concentration to minimize the risks of both hypoxemia and hyperoxemia are the main goal related to mechanical ventilation in hospitalized premature infants (1)(2)(3)(4).…”

Section: Introductionmentioning

confidence: 99%

Designing a Remote Closed-Loop Automatic Oxygen Control in Preterm Infants

et al. 2020

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Background: Different automated systems have been developed to improve the maintenance of target range of arterial oxygen saturation (SPO2) in premature infants with respiratory distress. Objectives: This study aimed to develop a remote closed-loop automatic oxygen control (RCLAC) as an efficient monitoring device. Then the means of the fraction of inspired oxygen (FIO2) and SPO2 by routine manual control (RMC) and RCLAC were compared. Methods: A developmental-descriptive study was carried out in an Iranian hospital (Tehran, Iran; 2015 - 2017). Twenty-two preterm infants with gestational age 24 - 28 weeks entered the study. A database was prepared based on pulse oximeter parameters. A Wi-Fi module was implemented to receive data from a pulse oximeter and send inputs to the user’s mobile. Vibrate alarm was implemented for high or low FIO2. After receiving notifications associated with an increase or decrease of FIO2 levels and user’s confirmation; the alterations were applied on the ventilator. Results: The mean FIO2 in the RMC system was significantly higher than the RCLAC system (98.1 ± 2.67 vs 79.5 ± 16.03; P = 0.0001). According to the results, when the SPO2 reached close to target SPO2 range and consequently FIO2 changed (decreased or increased based on target SPO2), heart rate showed a regular beating with a decrease in the numbers. Conclusions: Remote closed-loop automatic oxygen control system as a simple device could prevent preterm neonates from sustained hypo-hyperoxemic and arrhythmia episodes. Moreover, by using RCLAC, there was no need for continuous monitoring that may reduce the workload of NICU medical staff. Collecting reliable data and recording information in digital forms were also other benefits. Further studies with larger sample size are strongly suggested.

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