2024
DOI: 10.21203/rs.3.rs-3846667/v1
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Oxymatrine Modulation of TLR3 Signaling Pathway: A Dual-Action Mechanism against H9N2 Avian Influenza Virus and Immune Regulation

Yan Zhi,
Zhenyi Liu,
Guo Shen
et al.

Abstract: Background H9N2 Avian Influenza Virus (AIV) poses a growing public health threat due to its rapid mutation rate and limited vaccine efficacy. Pulmonary Microvascular Endothelial Cells (PMVECs) play a critical role as a gateway for infection, highlighting the need for alternative therapeutic strategies. This study examines the antiviral potential of Oxymatrine (OMT), a traditional Chinese medicine derivative, against H9N2 AIV in PMVECs. Purpose The aim of this study is to explore the efficacy of OMT in modulati… Show more

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