Oxytocin and Uterine Atony during Cesarean Section

Abstract

In our medical practice, in particular obstetrics, it is difficult to change certain consolidated dogmas, but the necessity and the current situation of our obstetrical exercise pushed us to find new technical supports, to make the exercise of our specialty as stripped of pitfalls as possible. Our work is summarized in a prospective comparative study, aimed at evaluating the existence or not of a difference between the administration of oxytocin just before the hysterotomy in a cesarean section and its administration after fetal extraction. We used a set of criteria to include patients in our study. This study took place over a period of one year (2020) in the Mother and Child regional center, in Meknes Imperial city, Morocco, involving a total number of 364 patients. With a group A comprising 176 patients 48% (176/364) who received oxytocin just before the hysterotomy and a group B of 188 patients 52% (188/364) who received it classically after fetal extraction. The difference was very significant as detailed in the article. Conclusion: the very convincing results of our study and the difference between the two groups, allowed us to demonstrate the effectiveness of our process and to endorse its use in our routine practice, with the perspective of conducting a prospective randomized study on a larger series.

Cohort Study Summary of the Effects of Carboprost Tromethamine Combined with Oxytocin on Infant Outcome, Postpartum Hemorrhage and Uterine Involution of Parturients Undergoing Cesarean Section

“…Because PG is widely distributed in human tissues, it plays a good role in uterine smooth muscle and vasoconstriction. It is able to take effect quickly after intramuscular injection and further enhances the contractile effect of uterine smooth muscle by increasing the amplitude and frequency of uterine contraction [ 13 , 14 ]. Based on this, this study focuses on the effects of carboprost tromethamine combined with oxytocin on infant outcome, postpartum hemorrhage, and uterine involution after cesarean section.…”

Oxytocin Abuse and Postpartum Hemorrhage

“…-Concerning, pain, we notice that it was less felt in the first group than in the second group, which suggests that oxytocin and because of its amplifying effect on uterine contractions [12] [13] [14] [15], increases the painful sensation of the uterine contractions. This represents an additional positive point in favor of the protocol used in the 1st group, especially after collecting the opinions of the patients, who were not traumatized by the experience of their childbirth, contrary to what is described in the literature [16] [17] and [18].…”