Oxytocin as Stimulator for the Release of Prolactin from the Anterior Pituitary

Benson, G. K.; Folley, S. J.

doi:10.1038/177700a0

Cited by 68 publications

(39 citation statements)

References 4 publications

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“…Although our results imply a clear dissociation between PRL or CORT release and OT release, this phenomenon is not in agreement with at least two other reports that demonstrated that PRL release may be stimulated by OT during suckling [3,32]. Under identical stimulation (suckling) of ascending neural pathways, our results would suggest that OT release from the posterior pituitary is not a prerequisite for PRL and ACTH release from the anterior pituitary at time of udder stimulation.…”

Section: Discussioncontrasting

confidence: 47%

The effect of a mixed-management system on the release of oxytocin, prolactin, and cortisol in ewes during suckling and machine milking

Marnet¹,

Negrão²

2000

Reprod. Nutr. Dev.

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-Milk yield and plasma oxytocin (OT), prolactin (PRL), and cortisol (CORT) during suckling and machine milking were measured in multiparous ewes subjected to a mixed management system of 3 sucklings and two daily milkings. Peak hormones were significantly increased and were similar during suckling and milking for PRL (181 vs. 163.3 ng·mL -1 ) and CORT (12.5 vs. 11.5 ng·mL -1 ). During the period of exclusive suckling, OT was always significantly released (90.3 pg . mL -1 ); however, during the period of mixed management, OT concentrations only increased during suckling compared to milking (91.7 vs. 13.1 pg·mL -1 ). The mean volume of milk obtained during suckling (632 mL) was significantly higher than during milking (255 mL). Thus, during a mixed management system, oxytocin and prolactin releases are not under similar central regulation. A mixed system, without OT release during milking, does not contribute to accelerate the conditioning of ewes for machine milking.

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Section: Discussioncontrasting

confidence: 47%

The effect of a mixed-management system on the release of oxytocin, prolactin, and cortisol in ewes during suckling and machine milking

Marnet¹,

Negrão²

2000

Reprod. Nutr. Dev.

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“…It is well established that suckling and milking cause the release from the posterior pituitary of oxytocin, which produces milk ejection. Benson and F olley [1] suggested that this release of oxytocin in turn causes the release from the anterior pituitary of prolactin, which helps to maintain milk secretion. We have tested this hypothesis on 9 occasions and obtained some suggestion of an increased rate of release of prolactin in 7.…”

Section: Resultsmentioning

confidence: 99%

Plasma Prolactin in Goats Measured by Radioimmunoassay: The Effects of Teat Stimulation, Mating Behavior, Stress, Fasting and of Oxytocin, Insulin and Glucose Injections

Bryant¹,

Linzell²,

Greenwood³

1970

Horm Res Paediatr

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Results are reported of measuring prolactin in goatplasma by a radioimmunoassay.Changes in concentration in plasma prolactin over time scales from minutes to hours were noted in animals not subject to experimental stimuli. It is presumed that these changes reflect the rapid removal of prolactin from plasma (t ½ 19 min) and the secretion of prolactin in response to unknown internal stimuli. Stimuli are reported which cause rises in plasma concentration suggestive of bursts of secretion from the pituitary. Copulation, in both males and females, sexual excitement in males and milking caused the largest increases in plasma concentration. Oxytocin injections and mild stress caused significant but smaller increases in plasma prolactin sometimes seen as a rise in jugular vein concentrations only. Plasma prolactin fell on fasting and after insulin and it rose on refeeding, but there was not a direct correlation with changes in blood glucose concentration.

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“…The measurement of prolactin levels in blood collected throughout par¬ turition presented an ideal opportunity to test, in a physiological situation, the validity of the hypothesis that in certain circumstances oxytocin may stimulate the release of prolactin from the anterior pituitary (Benson & Folley, 1956 Despite extremely large increases in the concentration of oxytocin (2 to 745 pg/ml), the increases in the circulating level of prolactin were relatively small in comparison with the magnitude of the release that usually occurs at milking (Bryant, Greenwood & Linzell, 1968;Johke, 1969;Hart, 1972b) when the quantity of oxytocin released is often less than that released during parturition (Folley & Knaggs, 1965;McNeilly, 1972 Hart, 1973b). The average levels determined in blood samples taken at 30 min intervals throughout a single 24 hr period were higher in four castrated males than those measured in four virgin females.…”

mentioning

confidence: 99%

The Relationship Between Lactation and the Release of Prolactin and Growth Hormone in the Goat

Hart¹

1974

Reproduction

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Oxytocin as Stimulator for the Release of Prolactin from the Anterior Pituitary

Cited by 68 publications

References 4 publications

The effect of a mixed-management system on the release of oxytocin, prolactin, and cortisol in ewes during suckling and machine milking

The effect of a mixed-management system on the release of oxytocin, prolactin, and cortisol in ewes during suckling and machine milking

Plasma Prolactin in Goats Measured by Radioimmunoassay: The Effects of Teat Stimulation, Mating Behavior, Stress, Fasting and of Oxytocin, Insulin and Glucose Injections

The Relationship Between Lactation and the Release of Prolactin and Growth Hormone in the Goat

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