Ozonation and Photo-Driven Oxidation
of Ciprofloxacin in Pharmaceutical Wastewater:
Degradation Kinetics and Energy Requirements

Wajahat, Rabia; Yasar, Abdullah; Khan, Ali Haider; Tabinda, Amtul Bari; Bhatti, Sumera Gul

doi:10.15244/pjoes/90597

Cited by 25 publications

(9 citation statements)

References 21 publications

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“…The product at [M+H] + = 306 is devinylciprofloxacin, caused by the net loss Several current methods for the degradation of ciprofloxacin were compared in the study, as shown in Table 2. It can be seen that the effect of the photocatalytic method is poor [69], but the degradation of ciprofloxacin by the Fenton oxidation and the ozone oxidation method in the advanced oxidation method is very good, and the degradation rate can reach more than 70%, The ozonation process even reached 98.7% [70,71]. However, many studies have been carried out under low ciprofloxacin concentration, and some of the catalysts cannot be recycled.…”

Section: Mechanism Of Ciprofloxacin Degradation By Fe2o3/rgo-atp Catamentioning

confidence: 99%

A Novel Reduced Graphene Oxide-Attapulgite (RGO-ATP) Supported Fe2O3 Catalyst for Heterogeneous Fenton-like Oxidation of Ciprofloxacin: Degradation Mechanism and Pathway

et al. 2020

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Ciprofloxacin, a third-generation fluoroquinolones (FQs) antibiotic, is observed to increasingly pollute the environment. In this study, a three-dimensional reduced graphene oxide-attapulgite-based catalyst Fe2O3/RGO-ATP was prepared and used to analyze the degradation of ciprofloxacin in a heterogeneous Fenton reaction. The heterogeneous catalyst Fe2O3/RGO-ATP was prepared by a one-step hydrothermal method, and the samples were characterized using BET(Brunauer-Emmett-Teller) surface area, Raman spectroscopy, X-ray diffraction (XRD), Fourier infrared (FTIR) spectroscopy, scanning electron microscopy (SEM) and X-ray photoelectron spectroscopy (XPS). The effect of reaction time, temperature, pH, initial concentration, H2O2 dosage and reuse time on the degradation of ciprofloxacin by the catalyst Fe2O3/RGO-ATP was investigated. The optimum conditions of degradation of ciprofloxacin are observed to be 60 °C, pH 5, H2O2 concentration of 2.9724 mmol/L, and initial ciprofloxacin concentration of 50 mg/L. The catalyst could be reused several times with a decline in catalytic capacity. Fourier-transform ion cyclotron resonance mass spectrometer (FT) was also employed to study the degradation products of ciprofloxacin in the aqueous solution. The results show that the heterogeneous catalyst Fe2O3/RGO-ATP possessed an excellent ability for the catalytic degradation of ciprofloxacin. Direct hydroxyl oxidation is noted to be the main pathway of degradation of ciprofloxacin, and no defluorination reaction is observed during the degradation process.

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Section: Mechanism Of Ciprofloxacin Degradation By Fe2o3/rgo-atp Catamentioning

confidence: 99%

A Novel Reduced Graphene Oxide-Attapulgite (RGO-ATP) Supported Fe2O3 Catalyst for Heterogeneous Fenton-like Oxidation of Ciprofloxacin: Degradation Mechanism and Pathway

et al. 2020

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“…It is believed that around 40–90% of the prescribed antibiotic dose (depending on the class of pharmaceutical) is excreted as a parent compound in the active form in the feces and urine, and when it finally reaches the environment it causes soil, water, and plant contamination [ 19 , 20 , 21 ]. The use of excessive doses of antibiotics in livestock farming can pollute agro-ecosystems through either the application of contaminated manure as fertilizer in agriculture, or the irrigation of farms with wastewater [ 22 , 23 ]. Another source of concern comprises the improper disposal of leftover, expired, or unused pharmaceuticals which are released into sewage systems [ 24 ].…”

Section: Introductionmentioning

confidence: 99%

A Review of Methods for Removal of Ceftriaxone from Wastewater

Karungamye

Rugaika

Mtei

et al. 2022

JoX

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The presence of pharmaceuticals in surface water and wastewater poses a threat to public health and has significant effects on the ecosystem. Since most wastewater treatment plants are ineffective at removing molecules efficiently, some pharmaceuticals enter aquatic ecosystems, thus creating issues such as antibiotic resistance and toxicity. This review summarizes the methods used for the removal of ceftriaxone antibiotics from aquatic environments. Ceftriaxone is one of the most commonly prescribed antibiotics in many countries, including Tanzania. Ceftriaxone has been reported to be less or not degraded in traditional wastewater treatment of domestic sewage. This has piqued the interest of researchers in the monitoring and removal of ceftriaxone from wastewater. Its removal from aqueous systems has been studied using a variety of methods which include physical, biological, and chemical processes. As a result, information about ceftriaxone has been gathered from many sources with the searched themes being ceftriaxone in wastewater, ceftriaxone analysis, and ceftriaxone removal or degradation. The methods studied have been highlighted and the opportunities for future research have been described.

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“…Fluoroquinolones (FQs) are among the main classes of antimicrobial pharmaceuticals widely used in both human and veterinary medicine. FQs as ciprofloxacin (CIP), gatifloxacin (GAT), ofloxacin (OFL) and norfloxacin (NOR) have been reported at ranging levels from ng L À1 to μg L À1 , in the most diverse aquatic environments (e.g., hospital wastewater, pharmaceutical industry and urban wastewater, and surface water) (Wang et al 2010;Jia et al 2012;Rodrigues-Silva et al 2019;Wajahat et al 2019).…”

Section: Introductionmentioning

confidence: 99%

Evaluation of residual antimicrobial activity and acute toxicity during the degradation of gatifloxacin by ozonation

Caianelo

Rodrigues-Silva

Maniero

et al. 2021

Water Science and Technology

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The concerns regarding the occurrence of pharmaceuticals in wastewater treatment plants have been increased in the last decades. Gatifloxacin (GAT), the fourth generation of fluoroquinolones, has been widely used to treat both Gram-positive and Gram-negative bacteria and has a limited metabolization. The present study aimed to evaluate the ozonation as a technique to degrade GAT. A UHPLC-MS/MS method was used to quantify the residual of GAT and to assess its degradation products. The removal efficiency was higher at alkaline condition (pH = 10), reaching up to 99% of GAT after 4 min. It was also observed that the first ozone attack on the GAT molecule was through the carboxylic group. In contrast, at acid conditions (pH = 3), the ozone attack was first to the piperazinyl ring. The antimicrobial activity was evaluated using Escherichia coli and Bacillus subtilis as test organisms, and it was observed that the residual activity reduced most at the alkaline conditions. In contrast, the best condition to remove the residual toxicity evaluated for the marine bacteria V. fischeri was the acidic one. Due to this, the ozonation seemed to be an exciting process to remove GAT at aqueous media.

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Ozonation and Photo-Driven Oxidation of Ciprofloxacin in Pharmaceutical Wastewater: Degradation Kinetics and Energy Requirements

Cited by 25 publications

References 21 publications

A Novel Reduced Graphene Oxide-Attapulgite (RGO-ATP) Supported Fe2O3 Catalyst for Heterogeneous Fenton-like Oxidation of Ciprofloxacin: Degradation Mechanism and Pathway

A Novel Reduced Graphene Oxide-Attapulgite (RGO-ATP) Supported Fe2O3 Catalyst for Heterogeneous Fenton-like Oxidation of Ciprofloxacin: Degradation Mechanism and Pathway

A Review of Methods for Removal of Ceftriaxone from Wastewater

Evaluation of residual antimicrobial activity and acute toxicity during the degradation of gatifloxacin by ozonation

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