P-029 Severity of Inflammatory Bowel Disease Hospitalizations Varies According to Age and Gender

Brandon, W.J.M.; Seminerio-Diehl, Jennifer; Galandiuk, Susan; Rockey, Don

doi:10.1097/01.mib.0000456750.46035.18

Cited by 1 publication

(8 citation statements)

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“…Among these, 125 studies were excluded (Figure ). Therefore, six studies that included a total of 741 743 patients were selected for full analysis (Table ). There were two record‐linkage clinical studies, three data‐based studies and one study based upon a nationwide audit .…”

Section: Resultsmentioning

confidence: 99%

“…Therefore, six studies that included a total of 741 743 patients were selected for full analysis (Table ). There were two record‐linkage clinical studies, three data‐based studies and one study based upon a nationwide audit . Four studies reported 3‐month mortality, one study reported 12‐month mortality, and one study reported both 3‐ and 12‐month mortalities of ASUC.…”

Section: Resultsmentioning

confidence: 99%

“…There were two record‐linkage clinical studies, three data‐based studies and one study based upon a nationwide audit . Four studies reported 3‐month mortality, one study reported 12‐month mortality, and one study reported both 3‐ and 12‐month mortalities of ASUC. There were three European studies, all from the United Kingdom, and three studies performed in the United States of America.…”

Section: Resultsmentioning

confidence: 99%

“…Four studies reported 3‐month mortality, one study reported 12‐month mortality, and one study reported both 3‐ and 12‐month mortalities of ASUC. There were three European studies, all from the United Kingdom, and three studies performed in the United States of America. Three studies were presented as conferences abstracts …”

Section: Resultsmentioning

confidence: 99%

“…There were three European studies, all from the United Kingdom, and three studies performed in the United States of America. Three studies were presented as conferences abstracts …”

Section: Resultsmentioning

confidence: 99%

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Systematic review with meta‐analysis: mortality in acute severe ulcerative colitis

Dong

Metzger

Holsbø

et al. 2019

Aliment Pharmacol Ther

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Summary Background Acute severe ulcerative colitis (ASUC) is a life‐threatening condition. Mortality in ASUC decreased in published series but there is uncertainty as to whether this also applies to the real‐life setting. Aim To perform a systematic review and meta‐analysis of mortality in ASUC in studies from referral centres and in population‐based studies, separately and combined. A second aim was to identify risk factors of mortality in ASUC. Methods We searched pubmed and embase from 1998 to 2016, to identify studies that reported 3‐month or 12‐month mortalities of acute UC in adult patients treated in referral centres, and in population‐based studies. Results Six population‐based studies with 741 743 patients and 47 referral centre‐based studies with 2556 patients were included. The pooled 3‐month and 12‐month mortalities were respectively 0.84% and 1.01%. Advanced age was significantly associated with both 3 month and 12 month mortalities (OR = 1.15 per year, 95% CI: 1.10‐1.20 and OR = 1.19 per year, 95% CI: 1.15‐1.23 respectively). The pooled 3‐month and 12‐month mortalities were 0.78% and 0.85% in studies with median age of less than 50 and 2.81% and 4.17% in studies with median age of 50 or more, respectively. After adjustment for age, 3‐month and 12‐month mortalities did not differ between population‐based and referral centre‐based studies. Conclusions Mortality in acute severe ulcerative colitis is approximately 1%; it is higher in older patients. Efforts should be made to improve the care of elderly patients with severe UC.

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Section: Resultsmentioning

confidence: 99%

Section: Resultsmentioning

confidence: 99%

Section: Resultsmentioning

confidence: 99%

Section: Resultsmentioning

confidence: 99%

“…There were three European studies, all from the United Kingdom, and three studies performed in the United States of America. Three studies were presented as conferences abstracts …”

Section: Resultsmentioning

confidence: 99%

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