P.03.3 Epidemiology of Autoimmune Pancreatitis in Italy: Results of Snapa Survey

Type 2 autoimmune pancreatitis associated with ulcerative colitis

“…The prevalence of UC in type 2 AIP reported in recent studies ranges from 16%-83% (25-27, 38, 57, 59, 61-68), as shown in Table 1. Among these, the studies by Detlefsen et al results differed significantly for the following possible reasons: Barresi et al's study (62) was a national survey that included 173 centres and the diagnosis of AIP was based on the independent judgement of each centre, whereas Conti et al's study (26) was a single-centre study, so the heterogeneity of diagnosis was different between the two studies. In addition, about three times as many cases of type 2 AIP were histologically examined in the study of Barresi et al (62) than that of Conti et al (26), and the majority of type 2 AIP cases in Conti et al's study were probable diagnoses (26), which may have contributed to the high prevalence of type 2 AIP.…”

“…A multicentre retrospective study in Italy reported that 31% of patients with type 2 AIP had pancreatic atrophy, 8% had diabetes mellitus (DM), and 10% had pancreatic calcification after 2-3 years of follow-up (62). After 4-5 years of follow-up of patients with type 2 AIP-IBD, it was found that approximately 19%-28% of patients had pancreatic exocrine insufficiency, and 12%-17% of patients had DM (9,59).…”