P-16 Lung cancer chemoterapy and 12 leads EKG telemetry: Preliminary EKG data

Trivellato, M; Cartei, G.; Pastorelli, Davide; Ceravolo, R.; Canton, Rosanna; Buratin, Lorena; Bano, Claudio

doi:10.1016/s0169-5002(03)91985-4

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Twelve-diagnostic Leads Te-lemetry (Tdlt)1

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2010

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“…We firstly studied prospectively some aspects of cardiac toxicity in patients during gemcitabine chemotherapy infusion for non-small cell lung cancer (NSCLC) [2]. Seventeen patients were evaluated, 12 male and 5 female, median age was 63 years (range 37-84) and ECOG (Eastern Cooperative Oncology Group) performance status was 0 in 12 patients and 1 in 5.…”

Section: Twelve-diagnostic Leads Te-lemetry (Tdlt)mentioning

confidence: 99%

Cardio-Toxicity during chemotherapy: feasibility of new diagnostic approaches

Zustovich¹,

Trivellato²,

Ceravolo³

et al. 2010

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Chemotherapy induced cardio-toxicity is a well known side effect of anticancer treatments, moreover the 70% of all tumors involve patients over 65 years-old, frequently with cardiac co- morbidity. We evaluated the feasibility of the application during chemotherapy administration of some of the most recent diagnostic techniques as 12-diagnostic leads telemetry, 7 days EKG monitoring device (R-Test Evolution 3R), blood level dosage of Brain Natriuretic Peptide (BNP) and Ischemia Modified Albumin (IMA). Some sub-clinical changes in the investigated parameters were found in patients undergoing chemotherapy, mostly containing fluorouracil, as shown in the following paper. Far from suggesting a widespread use of these methods during chemotherapy administration, we think that some more tools are needed to prevent cardiac toxicity in high-risk patients and some of what we studied may deserve further valuation in chemotherapy clinical trials

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Section: Twelve-diagnostic Leads Te-lemetry (Tdlt)mentioning

confidence: 99%