P.2.h.013 Depression and glycemic control in a sample of patients with type 2 diabetes

Abuhegazy, Hesham; Elkeshishi, H.; Farrag, Hesham A; Saleh, Natifah Che

doi:10.1016/s0924-977x(14)70768-0

European Neuropsychopharmacology

2014

DOI: 10.1016/s0924-977x(14)70768-0

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P.2.h.013 Depression and glycemic control in a sample of patients with type 2 diabetes

Hesham Abuhegazy¹,

H. Elkeshishi²,

Hesham A Farrag³

et al.

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Prevalence of comorbid major depressive disorder in Type 2 diabetes: a meta‐analysis of comparative and epidemiological studies

Wang

Zong³

et al. 2019

Diabet. Med.

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Aims To examine the average point prevalence of major depressive disorder in people with Type 2 diabetes and its associated factors in a comprehensive meta‐analysis. Methods Two researchers independently conducted a systematic literature search of PubMed, EMBASE, PsycINFO and Cochrane databases. Studies reporting the prevalence of major depressive disorder in people with Type 2 diabetes were identified and analysed using a random‐effects model. Results A total of 26 studies meeting the inclusion criteria were included in the study. The point prevalence of major depressive disorder was 14.5% (95% CI 7.9–25.3; I²=99.65). People with Type 2 diabetes were more likely to have major depressive disorder compared with the general population (odds ratio 1.73, 95% CI 1.38–2.16). Subgroup and meta‐regression analyses showed that study site, study type, diagnostic criteria and age significantly moderated the prevalence of major depressive disorder. Conclusions In this meta‐analysis, the average point prevalence of major depressive disorder in people with Type 2 diabetes was high. Routine screening and more effective interventions should be implemented for this population.

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Prevalence of comorbid major depressive disorder in Type 2 diabetes: a meta‐analysis of comparative and epidemiological studies

Wang

Zong³

et al. 2019

Diabet. Med.

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Glycemic Control among Patients with Diabetes and Comorbid Depression in Gulf Countries

Alsaad

Binmoammar

Hassounah

et al. 2021

Journal of Nature and Science of Medicine

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Background: People with diabetes suffering from depression are at greater risk of suffering from an episode of diabetic burnout which can have adverse outcomes on their health. Objectives: The primary objective is to review the relationship between depression and glycemic control among patients with diabetes in the Gulf Cooperation Council (GCC) countries. Methods: MEDLINE, EMBASE, PsychINFO, and GLOBAL HEALTH databases were systematically searched without language restriction to identify relevant studies that examined the relationship between glycemic control and depression among patients with diabetes in (GCC) countries. Reference lists and Google Scholar were also searched for additional studies. Research was conducted by two reviewers independently and disagreements were resolved by discussion. Results: Our search revealed nine studies were published between 2004 and 2018 and a total of 2199 subjects with diabetes. Majority of the participants were diagnosed with type 2 diabetes mellitus (DM). Out of the 9 articles included in the synthesis, only five of them have reported a significant association between depression and glycemic control; on the other hand, four articles showed nonsignificant association. The prevalence rates of depression among diabetic patients ranged from 12.5% to 61.8%. Conclusion: Depression was associated with poorly controlled HbA1c. However, this association was not significant across all studies. Considering the high rates of DM in these countries, better quality studies are needed to assess the depression comorbidity and its impact on glycemic control for better cost-effective treatments and to inform practice.

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P.2.h.013 Depression and glycemic control in a sample of patients with type 2 diabetes

Cited by 2 publications

References 0 publications

Prevalence of comorbid major depressive disorder in Type 2 diabetes: a meta‐analysis of comparative and epidemiological studies

Prevalence of comorbid major depressive disorder in Type 2 diabetes: a meta‐analysis of comparative and epidemiological studies

Glycemic Control among Patients with Diabetes and Comorbid Depression in Gulf Countries

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