P0098 Association of special dietary habits with aberrant methylation of p16, E-cadherin, and hMLH1 genes in gastric carcinoma in Kashmir valley, India

Banday, Manzoor Ahmad; Alam, Khursheed; Mir, Manzoor Ur Rahman

doi:10.1016/j.ejca.2015.06.059

European Journal of Cancer

2015

DOI: 10.1016/j.ejca.2015.06.059

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P0098 Association of special dietary habits with aberrant methylation of p16, E-cadherin, and hMLH1 genes in gastric carcinoma in Kashmir valley, India

Manzoor Ahmad Banday

Khursheed Alam

Manzoor Ur Rahman Mir

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“…The incidence is significantly elevated in Eastern Asia, compared with North America and Europe (1) . Increasing evidence has shown that gastric cancer was induced by synergistic effects of Helicobacter pylori infection, dietary factors and genetic instability (2)(3)(4) . Since H. pylori eradication has been applied, the morbidity of gastric cancer has decreased (5) .…”

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confidence: 99%

Index-based dietary patterns in relation to gastric cancer risk: a systematic review and meta-analysis

et al. 2019

Br J Nutr

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Dietary indices are widely used in diet quality measurement, and the index-based dietary patterns are related to gastric cancer risk. To evaluate the relationship between different kinds of index-based dietary patterns and gastric cancer risk, we systematically searched four English-language databases and four Chinese-language databases. The quality of studies was assessed by the Newcastle–Ottawa Scale. Meta-analyses were performed to estimate the association between gastric cancer incidence and different types of index-based dietary patterns. The OR and hazard ratios (HR) of gastric cancer incidence were calculated by regression models in case–control studies and prospective cohort studies, respectively. The studies were pooled in the random effects model to calculate the summarised risk estimate of the highest quantile interval of dietary indices, taking the lowest as the referent. The dietary indices included different versions of Mediterranean diet score (MDS) and dietary inflammatory index (DII), healthy eating index, Chinese Food Pagoda score and food index score. The meta-analysis was carried out for studies on MDS and DII. The combined OR of gastric cancer for the highest MDS v. the referent was 0·42 (95 % CI 0·2, 0·86), and the combined HR was 0·89 (95 % CI 0·68, 1·17). The combined OR for DII was 2·11 (95 % CI 1·41, 3·15). Higher Mediterranean dietary pattern consumption might reduce gastric cancer risk, while higher inflammatory diet pattern consumption might increase gastric cancer risk.

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confidence: 99%

Index-based dietary patterns in relation to gastric cancer risk: a systematic review and meta-analysis

et al. 2019

Br J Nutr

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P0098 Association of special dietary habits with aberrant methylation of p16, E-cadherin, and hMLH1 genes in gastric carcinoma in Kashmir valley, India

Cited by 1 publication

References 0 publications

Index-based dietary patterns in relation to gastric cancer risk: a systematic review and meta-analysis

Index-based dietary patterns in relation to gastric cancer risk: a systematic review and meta-analysis

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