P0206 the Usefulness of Quantitative Analysis of Hepatocellular Function Determined by Deconvolutional Analysis in Neonatal Cholestasis

Kamińska, Agnieszka; Pawłowska, Joanna; Czubkowski, Piotr; Jankowska, Irena; Kamiński, Andrzej; Swiatek-Rawa, E.

doi:10.1097/00005176-200406001-00330

Cited by 1 publication

(1 citation statement)

References 0 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…However, they have different limitations. It was reported that radionuclide-imaging of liver and gallbladder can give false positive results, since there is a fully obstructive stage due to cholangitis or cholestasis in neonatal hepatitis syndrome and infantile hepatitis syndrome [6][7][8] . When there is deficient choleresis or the diameter of biliary tract is too small, they would be easily misdiagnosed as BA [9][10][11] .…”

Section: Discussionmentioning

confidence: 99%

Ultrasonic diagnosis of biliary atresia: A retrospective analysis of 20 patients

Zhang²,

Sun³

et al. 2008

WJG

View full text Add to dashboard Cite

AIM:To investigate the clinical value of ultrasonographic diagnosis of biliary atresia (BA), a retrospective analysis of the sonogram of 20 children with BA was undertaken. METHODS: Ultrasonography (US) was performed in 20 neonates and infants with BA, which was confirmed with cholangiography by operation or abdominoscopy. The presence of triangular cord, the size and echo of liver, the changes in empty stomach gallbladder and postprandial gallbladder were observed and recorded. RESULTS: The triangular cord could be observed at the porta hepatis (thickness: 0.3-0.6 cm) in 10 cases. Smaller triangular cord (0.2-0.26 cm) can be observed in 3 cases. The gallbladder was not observed in 2 cases, and 1 case showed a streak gallbladder without capsular space. The gallbladders of 15 cases were flat and small. The gallbladders of 2 cases were of normal size and appearance, however, there was no postprandial contraction. The livers of all cases showed hepatomegaly and heterogeneous echogenicity. Statistical analysis was performed to compare the hepatomegaly and heterogeneous echogenicity and the stage of hepatic fibrosis. CONCLUSION:The presence of the triangular cord at the porta hepatis is specific. However, it is not the only diagnostic criterion, since flat and small gallbladder and poor contraction are also of important diagnostic and differential diagnostic significance. The degree of hepatomegaly and heterogeneous echogenicity is proportional with liver fibrosis, and able to indicate the duration of course and prognosis.

show abstract

Section: Discussionmentioning

confidence: 99%