P1.181 Parkinson's Disease Psychosis (PDP): An under-diagnosed condition in spite of its prevalence and impact

Fernandez, Hubert; Lio, F.M.; Kaiser, Jocelyn; Davis, Priscilla; Peters, Perry; Williams, Hilde; Bahr, Daun; Mills, Reversa

doi:10.1016/s1353-8020(09)70303-7

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“…До введения в практику леводопы у пациентов с БП редко отмечались психические расстройства [19], поэтому традиционно считалось, что лечение антипаркинсоническими препаратами и деменция являются основной причиной ПРБП [20,21]. Однако результаты последующих исследований [3] поставили под сомнение это предположение.…”

Section: диагностика прпбunclassified

Modern approaches to treatment of psychosis in Parkinson’s disease

Cozac

2016

Z. nevrol. psikhiatr. im. S.S. Korsakova

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Psychotic disorders in Parkinson's disease (PDPD) are common and significantly influence the quality of life and disability level. The pathogenesis of PDPD is complex and not yet fully understood. Taking into consideration the features of the Parkinson's disease (usually older patients with a risk of cognitive decline), and the pharmacodynamics of the antiparkinsonian and traditional antipsychotic drugs, the management of PDPD is a challenging issue of clinical neurology and psychiatry. In this systematic review, scientific publications for the period 2014-2016 were analyzed within two bibliographic databases: MEDLINE/PubMed and eLIBRARY.RU. Additionally, the guidelines of the International Parkinson and Movement Disorders Society, American Academy of Neurology and European Academy of Neurology were included in the analysis. Clozapine is recommended to use in the treatment of PDPD, quetiapine is possible to use, pimavanserin will probably become a remedy of choice. Nonpharmacological approaches have positive effects on the general condition of the patients with PDPD, however the efficacy of such approaches to treat psychosis is unclear.

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Section: диагностика прпбunclassified

Modern approaches to treatment of psychosis in Parkinson’s disease

Cozac

2016

Z. nevrol. psikhiatr. im. S.S. Korsakova

View full text Add to dashboard Cite

show abstract

P1.181 Parkinson's Disease Psychosis (PDP): An under-diagnosed condition in spite of its prevalence and impact

Cited by 1 publication

References 0 publications

Modern approaches to treatment of psychosis in Parkinson’s disease

Modern approaches to treatment of psychosis in Parkinson’s disease

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