P1/HC-Pro, a Viral Suppressor of RNA Silencing, Interferes with Arabidopsis Development and miRNA Function

Kasschau, Kristin D.; Xie, Zhixin; Allen, Edwards; Llave, César; Chapman, Elisabeth J.; Krizan, Kate A.; Carrington, James C.

doi:10.1016/s1534-5807(03)00025-x

Cited by 870 publications

(758 citation statements)

References 52 publications

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“…In plants, several possible mechanisms are applied by the miRNA genes. In some cases, the pairing of an miRNA with its target gene transcript causes the cleavage of the transcript [5,20,21]. Plant miRNAs can also interfere with the ability of target transcripts in translation in a manner similar to animal miRNAs [6,22].…”

Section: Introductionmentioning

confidence: 99%

Evolution of plant microRNA gene families

Mao

2006

Cell Res

151

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MicroRNAs (miRNAs) are important post-transcriptional regulators of their target genes in plants and animals. miRNAs are usually 20-24 nucleotides long. Despite their unusually small sizes, the evolutionary history of miRNA gene families seems to be similar to their protein-coding counterparts. In contrast to the small but abundant miRNA families in the animal genomes, plants have fewer but larger miRNA gene families. Members of plant miRNA gene families are often highly similar, suggesting recent expansion via tandem gene duplication and segmental duplication events. Although many miRNA genes are conserved across plant species, the same gene family varies significantly in size and genomic organization in different species, which may cause dosage effects and spatial and temporal differences in target gene regulations. In this review, we summarize the current progress in understanding the evolution of plant miRNA gene families.

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Section: Introductionmentioning

confidence: 99%

Evolution of plant microRNA gene families

Mao

2006

Cell Res

151

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“…It is highly conserved in the plant kingdom and has been identified in 45 different plant species [12]. miR156 has been demonstrated to target SPL genes, which are plant specific transcription factors containing an SBP box [6,[13][14][15]. Recently, evolution of miRNA families with multiple members (such as miR156, miR169 and miR395) has been investigated in Arabidopsis.…”

Section: Introductionmentioning

confidence: 99%

Molecular evolution and selection of a gene encoding two tandem microRNAs in rice

et al. 2007

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It has been shown that overexpression of MIR156b/c resulted in a bushy phenotype in maize and rice. Our results indicated that the MIR156b/c locus was highly conserved among cereals, but not in dicots and that genome duplication events played an important role in the evolution of the miR156 family. Genetic diversity investigation at the locus indicated that only $9% of nucleotide diversity observed in wild rice (O. rufigogon) was maintained in the cultivated rice and the neutral model was rejected (P < 0.05) based on Tajima's D and Fu and Li's D * and F * tests. To our knowledge, this is the first example of miRNA gene to be targeted by both natural and domestication selection in plants.

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“…These are generated by RNase III-like enzymes from long primary transcripts encoded in intergenic regions (IGRs) or introns of the mRNA primary transcripts [5,[7][8][9]. Mature miRNAs can downregulate gene expression by pairing with messages of protein-coding genes to promote mRNA cleavage, or repression of productive translation upon incorporation into a ribonucleoprotein complex (miRNP) similar to the RNA-induced silencing complex (RISC) [10][11][12][13][14]. Indeed, the vast majority of the predicted or verified miRNA targets encode members of large families of transcription factors that regulate development [15].…”

Section: Introductionmentioning

confidence: 99%

Duplication and expression analysis of multicopy miRNA gene family members in Arabidopsis and rice

Jiang

Yin

et al. 2006

Cell Res

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To understand the expansion of multicopy microRNA (miRNA) families in plants, we localized the reported miRNA genes from Arabidopsis and rice to their chromosomes, respectively, and observed that 37% of 117 miRNA genes from Arabidopsis and 35% of 173 miRNA genes from rice were segmental duplications in the genome. In order to characterize whether the expression diversification has occurred among plant multicopy miRNA family members, we designed PCR primers targeting 48 predicted miRNA precursors from 10 families in Arabidopsis and rice. Results from RT-PCR data suggest that the transcribed precursors of members within the same miRNA family were present at different expression levels. In addition, although miR160 and miR162 sequences were conserved in Arabidopsis and rice, we found that the expression patterns of these genes differed between the two species. These data suggested that expression diversification has occurred in multicopy miRNA families, increasing our understanding of the expression regulation of miRNAs in plants.

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P1/HC-Pro, a Viral Suppressor of RNA Silencing, Interferes with Arabidopsis Development and miRNA Function

Cited by 870 publications

References 52 publications

Evolution of plant microRNA gene families

Evolution of plant microRNA gene families

Molecular evolution and selection of a gene encoding two tandem microRNAs in rice

Duplication and expression analysis of multicopy miRNA gene family members in Arabidopsis and rice

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